Chemistry and biology of multicomponent reactions
A Domling, W Wang, K Wang - Chemical reviews, 2012 - ACS Publications
Multicomponent reactions (MCRs) are one-pot reactions employing more than two starting
materials, for example, 3, 4,..., 7, where most of the atoms of the starting materials are …
materials, for example, 3, 4,..., 7, where most of the atoms of the starting materials are …
Recent developments in isocyanide based multicomponent reactions in applied chemistry
A Dömling - Chemical reviews, 2006 - ACS Publications
Multicomponent reactions (MCRs) are generally defined as reactions where more than two
staring materials react to form a product, incorporating essentially all of the atoms of the …
staring materials react to form a product, incorporating essentially all of the atoms of the …
The combinatorial synthesis of bicyclic privileged structures or privileged substructures
DA Horton, GT Bourne, ML Smythe - Chemical reviews, 2003 - ACS Publications
The exploration of privileged structures in drug discovery is a rapidly emerging theme in
medicinal chemistry. These structures represent a class of molecules capable of binding to …
medicinal chemistry. These structures represent a class of molecules capable of binding to …
" Multi-component reactions: emerging chemistry in drug discovery"'from xylocain to crixivan'
C Hulme, V Gore - Current medicinal chemistry, 2003 - ingentaconnect.com
With the recent emergence of combinatorial chemistry and high-speed parallel synthesis for
drug discovery applications, the multi-component reaction (MCR) has seen a resurgence of …
drug discovery applications, the multi-component reaction (MCR) has seen a resurgence of …
Recent advances in isocyanide-based multicomponent chemistry
A Dömling - Current Opinion in Chemical Biology, 2002 - Elsevier
Multicomponent reactions (MCRs) provide a powerful tool towards the one-pot synthesis of
diverse and complex compounds on the one hand and small and 'drug-like'heterocycles on …
diverse and complex compounds on the one hand and small and 'drug-like'heterocycles on …
[图书][B] Isocyanide chemistry: applications in synthesis and material science
V Nenajdenko - 2012 - books.google.com
The efficacy of isocyanide reactions in the synthesis of natural or naturallike products has
resulted in a renaissance of isocyanide chemistry. Now isocyanides are widely used in …
resulted in a renaissance of isocyanide chemistry. Now isocyanides are widely used in …
Isocyanide-based multicomponent reactions for the synthesis of heterocycles
Multicomponent reactions (MCRs) are extremely popular owing to their facile execution,
high atom-efficiency and the high diversity of products. MCRs can be used to access various …
high atom-efficiency and the high diversity of products. MCRs can be used to access various …
Recent developments in use of heteropolyacids, their salts and polyoxometalates in organic synthesis
Heteropolyacids, their salts and polyoxometalates have been used as catalysts in wide
range of organic reactions such as multi components, oxidation, reductions, electrochemical …
range of organic reactions such as multi components, oxidation, reductions, electrochemical …
Emerging molecular diversity from the intra-molecular Ugi reaction: iterative efficiency in medicinal chemistry
C Hulme, J Dietrich - Molecular diversity, 2009 - Springer
This review details a now established area within the isonitrile multi-component reaction
(IMCR) field of study, namely employing bi-functional reagents in the Ugi reaction for the …
(IMCR) field of study, namely employing bi-functional reagents in the Ugi reaction for the …
A versatile synthesis of fused triazolo derivatives by sequential Ugi/alkyne-azide cycloaddition reactions
I Akritopoulou-Zanze, V Gracias, SW Djuric - Tetrahedron letters, 2004 - Elsevier
We report a facile synthesis of fused dihydrotriazolo [1, 5-a] pyrazinones and
triazolobenzodiazepines by an Ugi/alkyne–azide cycloaddition synthetic sequence. The …
triazolobenzodiazepines by an Ugi/alkyne–azide cycloaddition synthetic sequence. The …