TRPV1 channels in cardiovascular system: a double edged sword?

PK Randhawa, AS Jaggi - International journal of cardiology, 2017 - Elsevier
Apart from modulating nociception, there is vital role of TRPV 1 channels in modulating
atherosclerosis, congestive heart failure, systemic hypertension, pulmonary hypertension …

Quercetin attenuates cardiomyocyte apoptosis via inhibition of JNK and p38 mitogen-activated protein kinase signaling pathways

C Li, T Wang, C Zhang, J Xuan, C Su, Y Wang - Gene, 2016 - Elsevier
Abstract Quercetin (Que), a plant-derived flavonoid, possesses various biological functions.
Moreover, Que exerts multiple beneficial actions in treatment of cardiovascular diseases and …

Polydatin protects diabetic heart against ischemia‐reperfusion injury via Notch1/Hes1‐Mediated activation of Pten/Akt signaling

L Yu, Z Li, X Dong, X Xue, Y Liu, S Xu… - Oxidative Medicine …, 2018 - Wiley Online Library
Diabetes exacerbates oxidative/nitrative stress during myocardial ischemia‐reperfusion
(MI/R) injury. Recent studies highlighted the cardioprotective actions of polydatin. However …

Pterostilbene protects against myocardial ischemia/reperfusion injury via suppressing oxidative/nitrative stress and inflammatory response

Z Yu, S Wang, X Zhang, Y Li, Q Zhao, T Liu - International …, 2017 - Elsevier
Recent studies have shown that pterostilbene (Pte) confers protection against myocardial
ischemia/reperfusion injury. The oxidative/nitrative stress and inflammation induce injury …

Honokiol post-treatment ameliorates myocardial ischemia/reperfusion injury by enhancing autophagic flux and reducing intracellular ROS production

Z Tan, H Liu, X Song, Y Ling, S He, Y Yan, J Yan… - Chemico-Biological …, 2019 - Elsevier
Honokiol (HKL) is a natural low-molecular-weight biphenolic compound derived from the
bark of magnolia trees. Previous studies indicate that HKL exerts potent cardioprotective …

[HTML][HTML] Dose-Dependent Effects of Long-Term Administration of Hydrogen Sulfide on Myocardial Ischemia–Reperfusion Injury in Male Wistar Rats: Modulation of …

S Jeddi, S Gheibi, K Kashfi, M Carlström… - International journal of …, 2020 - mdpi.com
Decreased circulating levels of hydrogen sulfide (H2S) are associated with higher mortality
following myocardial ischemia. This study aimed at determining the long-term dose …

17-Methoxyl-7-hydroxy-benzene-furanchalcone ameliorates myocardial ischemia/reperfusion injury in rat by inhibiting apoptosis and autophagy via the PI3K–Akt …

F Xuan, J Jian, X Lin, J Huang, Y Jiao, W Huang… - Cardiovascular …, 2017 - Springer
Methoxyl-7-hydroxy-benzene-furanchalcone (MHBFC), a monomer isolated from the root of
Millettia pulchra (Benth.) Kurz var. Laxior (Dunn) Z. Wei (Papilionaceae), has been …

[HTML][HTML] Effects of nitrate intake on myocardial ischemia-reperfusion injury in diabetic rats

S Jeddi, S Khalifi, M Ghanbari, F Bageripour… - Arquivos brasileiros de …, 2016 - SciELO Brasil
Background: Coronary artery disease is 2-3 times more common in diabetic individuals.
Dietary nitrate/nitrite has beneficial effects in both diabetes and cardiovascular disease. It …

[HTML][HTML] Endoplasmic reticulum stress inhibition ameliorated WFS1 expression alterations and reduced pancreatic islets' insulin secretion induced by high-fat diet in …

F Binayi, J Fahanik-Babaei, M Salimi, F Eskandari… - Scientific Reports, 2023 - nature.com
Endoplasmic reticulum (ER) stress is involved in the development of glucose homeostasis
impairment. When ER stress occurs, the unfolded protein response (UPR) is activated to …

Role of inducible nitric oxide synthase in myocardial ischemia-reperfusion injury in sleep-deprived rats

S Jeddi, A Ghasemi, A Asgari, A Nezami-Asl - Sleep and Breathing, 2018 - Springer
Introduction REM sleep deprivation (SD) decreases tolerance of the rat heart to ischemia-
reperfusion (IR) injury; the underlying mechanisms, however, are unknown. This study …