Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches

JA Welsh, DCI Goberdhan, L O'Driscoll… - Journal of …, 2024 - Wiley Online Library
Extracellular vesicles (EVs), through their complex cargo, can reflect the state of their cell of
origin and change the functions and phenotypes of other cells. These features indicate …

The role and applications of extracellular vesicles in osteoporosis

F Fang, J Yang, J Wang, T Li, E Wang, D Zhang, X Liu… - Bone research, 2024 - nature.com
Osteoporosis is a widely observed condition characterized by the systemic deterioration of
bone mass and microarchitecture, which increases patient susceptibility to fragile fractures …

[HTML][HTML] A comprehensive review on recent advances in exosome isolation and characterization: Toward clinical applications

N Dilsiz - Translational Oncology, 2024 - Elsevier
Exosomes are small, round vesicles in the 30 and 120 nm diameter range released by all
living cell types. Exosomes play many essential functions in intercellular communication and …

Challenges associated with using extracellular vesicles as biomarkers in neurodegenerative disease

Y Couch - Expert Review of Molecular Diagnostics, 2023 - Taylor & Francis
Introduction The hunt for new biomarkers–for the diagnosis of subcategories of disease, or
for the monitoring of the efficacy of novel therapeutics–is an increasingly relevant challenge …

Improving the Purity of Extracellular Vesicles by Removal of Lipoproteins from Size Exclusion Chromatography-and Ultracentrifugation-Processed Samples Using …

CY Chou, PC Chiang, CC Li, JW Chang… - … Applied Materials & …, 2024 - ACS Publications
Extracellular vesicles (EVs) are present in blood at much lower concentrations (5–6 orders
of magnitude) compared to lipoprotein particles (LP). Because LP and EV overlap in size …

Proteomic Profiling of Plasma-and Gut-Derived Extracellular Vesicles in Obesity

P Baptista Pereira, E Torrejón, I Ferreira, AS Carvalho… - Nutrients, 2024 - mdpi.com
Obesity entails metabolic alterations across multiple organs, highlighting the role of inter-
organ communication in its pathogenesis. Extracellular vesicles (EVs) are communication …

Measurement of α-synuclein as protein cargo in plasma extracellular vesicles

T Gilboa, D Ter-Ovanesyan, SC Wang… - Proceedings of the …, 2024 - pnas.org
Extracellular vesicles (EVs) are released by all cells and hold great promise as a class of
biomarkers. This promise has led to increased interest in measuring EV proteins from both …

Confirming size-exclusion chromatography as a clinically relevant extracellular vesicles separation method from 1mL plasma through a comprehensive comparison of …

SD Robinson, M Samuels, W Jones, N Stewart… - BMC Methods, 2024 - Springer
Abstract Background Extracellular vesicles (EVs) are amongst the most promising
candidates for developing blood-based biomarkers. However, patient sample availability is …

Signal transduction pathways alter the molecular cargo of extracellular vesicles: Implications in regenerative medicine

P Teli, A Vaidya, V Kale - Regenerative Medicine, 2023 - Taylor & Francis
Extracellular vesicles (EVs) possess regenerative properties and are also considered as
future vaccines. All types of cells secrete EVs; however, the amount of EVs secreted by the …

Associations of age and sex with characteristics of extracellular vesicles and protein‐enriched fractions of blood plasma

Y Huang, J Feng, J Xu, L Dong, W Su, B Li… - Aging …, 2024 - Wiley Online Library
Extracellular vesicles (EVs) are nanosized particles that are released by various cell types
and play vital roles in intercellular communication. They carry biological molecules reflecting …