Morin as an imminent functional food ingredient: An update on its enhanced efficacy in the treatment and prevention of metabolic syndromes
K Thakur, YY Zhu, JY Feng, JG Zhang, F Hu… - Food & function, 2020 - pubs.rsc.org
Flavonoids represent polyphenolic plant secondary metabolites with a general structure of a
15-carbon skeleton comprising two phenyl rings and a heterocyclic ring. Over 5000 natural …
15-carbon skeleton comprising two phenyl rings and a heterocyclic ring. Over 5000 natural …
Alternative therapy of psychosis: Potential phytochemicals and drug targets in the management of schizophrenia
Schizophrenia is a chronic mental and behavioral disorder characterized by clusters of
symptoms including hallucinations, delusions, disorganized thoughts and social withdrawal …
symptoms including hallucinations, delusions, disorganized thoughts and social withdrawal …
Lipopolysaccharide exacerbates ketamine-induced psychotic-like behavior, oxidative stress, and neuroinflammation in mice: ameliorative effect of diosmin
Schizophrenia, a neuropsychiatric disorder has been associated with aberrant
neurotransmission affecting behaviors, social preference, and cognition. Limitations in …
neurotransmission affecting behaviors, social preference, and cognition. Limitations in …
Mechanisms underpinning Carpolobia lutea G. Don ethanol extract's neurorestorative and antipsychotic-like activities in an NMDA receptor antagonist model of …
Ethnopharmacological relevance Persistent ketamine insults to the central nervous system
block NMDA receptors and disrupt putative neurotransmission, oxido–nitrosative, and …
block NMDA receptors and disrupt putative neurotransmission, oxido–nitrosative, and …
Morin decreases cortical pyramidal neuron degeneration via inhibition of neuroinflammation in mouse model of schizophrenia
Neuroinflammation plays a prominent role in the pathophysiology and progression of
schizophrenia. Thus, suppression of neuroinflammation may retard the progression of the …
schizophrenia. Thus, suppression of neuroinflammation may retard the progression of the …
Repeated psychosocial stress causes glutamic acid decarboxylase isoform-67, oxidative-Nox-2 changes and neuroinflammation in mice: prevention by treatment with …
Psychosocial stress and biological predispositions are linked to mood and personality
disorders related to psychiatric behaviors. Targeting neuroinflammation and oxidative stress …
disorders related to psychiatric behaviors. Targeting neuroinflammation and oxidative stress …
[HTML][HTML] Probable mechanisms involved in the antipsychotic-like activity of morin in mice
Evidence derived from preliminary studies suggests that morin, a neuroactive flavonoid with
proven antioxidant and antiinflammatory properties possess antipsychotic-like activity. The …
proven antioxidant and antiinflammatory properties possess antipsychotic-like activity. The …
Involvement of GABAergic, BDNF and Nox-2 mechanisms in the prevention and reversal of ketamine-induced schizophrenia-like behavior by morin in mice
GABAergic (Gamma-aminobutyric acid) and neurotrophic derangements have important
implication in schizophrenia, a neuropsychiatric disease. Previous studies have shown that …
implication in schizophrenia, a neuropsychiatric disease. Previous studies have shown that …
Morin attenuates neurochemical changes and increased oxidative/nitrergic stress in brains of mice exposed to ketamine: prevention and reversal of schizophrenia-like …
Previous studies have revealed that morin (MOR), a neuroactive bioflavonoid, with proven
psychotropic and neuroprotective properties reduced schizophrenic-like behaviors in mice …
psychotropic and neuroprotective properties reduced schizophrenic-like behaviors in mice …
Effective action of silymarin against ketamine-induced schizophrenia in male mice: Insight into the biochemical and molecular mechanisms of action
B Ben-Azu, AR Fokoua, OS Annafi, OG Adebayo… - Journal of Psychiatric …, 2024 - Elsevier
Background Neurochemical dysregulations resulting from N-methyl-D-aspartate
hypofunction (NMDA), are exacerbated by neuroimmune and oxidative stress and are …
hypofunction (NMDA), are exacerbated by neuroimmune and oxidative stress and are …