Chronic kidney disease (CKD) is a worldwide public health problem. Patients with CKD
have a number of disorders in the organism, and the presence of oxidative stress and …

The high incidence of cardiovascular events in chronic kidney disease (CKD) warrants an
accurate evaluation of risk aimed at reducing the burden of disease and its consequences …

Background Decreased serum arylesterase activity, catalyzed by the high‐density
lipoprotein–associated paraoxonase (PON)‐1, is associated with increased oxidant stress …

In this review we summarize the findings from the literature and our own laboratory on the
decreased PON1 activity in renal failure, the mechanisms proposed and the effect of …

Oxidative stress is known to be associated with the pathophysiology of chronic kidney
disease (CKD). Paraoxonase 1 (PON1) is an antioxidant enzyme that has been proposed as …

Paraoxonase 1 (PON1) is an enzyme which is mainly synthesized in the liver. PON1
circulates in the blood bound to HDL and delays or prevents the oxidation of LDL. Single …

Patients with chronic kidney disease (CKD) are at high risk for CVD. However, traditional
lipid risk factors, including low HDL levels, cannot completely explain the increased risk …

BACKGROUND: Restless legs syndrome (RLS) is a common disorder in hemodialysis
patients that leads to insomnia and impaired quality of life. Because high oxidative stress …

Eur J Clin Invest 2011; 41 (7): 734–742 Abstract Background Oxidative stress has been
implicated in over 100 disorders in recent years; however, the situation in restless legs …

Chronic renal failure (CRF) is associated with the development of cardiovascular disease
(CVD). Paraoxonase 1 (PON1), an antioxidant enzyme, shows cardioprotective properties …