Molecular characterization of eight gastric cancer cell lines established in Japan are
summarized according to the genetic and epigenetic alterations and growth factor status …

Since the initial concept of p53 as a sensor of DNA-damage, the picture of the role of p53
has widened to include the sensing of much more diverse forms of stress, including hypoxia …

While testing purines related to the non‐specific protein kinase inhibitors N6‐
dimethylaminopurine and N6‐( 2‐isopentenyl) adenine as potential inhibitors of the …

The receptor for advanced glycation end‐products (RAGE) is a newly recognized factor
regulating cancer cell invasion and metastasis. This study investigated the expression of …

Gastric carcinoma (GC) is one of the most common malignancies worldwide. To better
understand the genetic basis of this disease, we performed serial analysis of gene …

Gastric cancer (GC) is one of the most common malignancies worldwide. Genes whose
expression is down‐regulated in GC may be tumour suppressor genes. In the present study …

We searched for genetic alterations of the cyclin D1 and cyclin E genes in 45 human gastric
carcinoma tissues. Expression of cyclin E mRNA and protein was also analyzed in eight of …

The novel compound 3-(1H-benzimidazol-2-yl)-5-isoquinolin-4-ylpyrazolo [1, 2-b] pyridine
was discovered to be a potent CDK1 inhibitor. Described here is the chemistry for its …

There is evidence to suggest that CDC25B phosphatase is an oncogenic protein. To
elucidate the role of CDC25B in colorectal carcinoma, we examined the expression of …

The mechanisms underlying peroxisome proliferator-induced hepatocarcinogenesis are
unclear but are mediated by the peroxisome proliferator-activated receptor alpha …