Glycomimetics for the inhibition and modulation of lectins

S Leusmann, P Ménová, E Shanin, A Titz… - Chemical Society …, 2023 - pubs.rsc.org
Carbohydrates are essential mediators of many processes in health and disease. They
regulate self-/non-self-discrimination, are key elements of cellular communication, cancer …

Glycobiology: toward understanding the function of sugars

RA Dwek - Chemical reviews, 1996 - ACS Publications
Glycobiology: Toward Understanding the Function of Sugars | Chemical Reviews ACS ACS
Publications C&EN CAS Find my institution Log In Chemical Reviews ACS Publications …

Phylogenetic perspectives in innate immunity

JA Hoffmann, FC Kafatos, CA Janeway Jr… - Science, 1999 - science.org
The concept of innate immunity refers to the first-line host defense that serves to limit
infection in the early hours after exposure to microorganisms. Recent data have highlighted …

The C‐type lectin‐like domain superfamily

AN Zelensky, JE Gready - The FEBS journal, 2005 - Wiley Online Library
The superfamily of proteins containing C‐type lectin‐like domains (CTLDs) is a large group
of extracellular Metazoan proteins with diverse functions. The CTLD structure has a …

Rationale for targeting complement in COVID‐19

A Polycarpou, M Howard, CA Farrar… - EMBO molecular …, 2020 - embopress.org
A novel coronavirus, SARS‐CoV‐2, has recently emerged in China and spread
internationally, posing a health emergency to the global community. COVID‐19 caused by …

Glycosylation and the immune system

PM Rudd, T Elliott, P Cresswell, IA Wilson, RA Dwek - Science, 2001 - science.org
Almost all of the key molecules involved in the innate and adaptive immune response are
glycoproteins. In the cellular immune system, specific glycoforms are involved in the folding …

Carbohydrate-protein interactions: basis of glycobiology

YC Lee, RT Lee - Accounts of chemical research, 1995 - ACS Publications
Glycobiology1 has become a popular topic in recent years when frontiers of biological
sciences are dis-cussed. Indeed, there are a number of important biological phenomena …

A transgenic model of visceral obesity and the metabolic syndrome

H Masuzaki, J Paterson, H Shinyama, NM Morton… - Science, 2001 - science.org
The adverse metabolic consequences of obesity are best predicted by the quantity of
visceral fat. Excess glucocorticoids produce visceral obesity and diabetes, but circulating …

Protein nanoparticles: uniting the power of proteins with engineering design approaches

N Habibi, A Mauser, Y Ko, J Lahann - Advanced Science, 2022 - Wiley Online Library
Protein nanoparticles, PNPs, have played a long‐standing role in food and industrial
applications. More recently, their potential in nanomedicine has been more widely pursued …

[HTML][HTML] Recent insights into structures and functions of C-type lectins in the immune system

K Drickamer, ME Taylor - Current opinion in structural biology, 2015 - Elsevier
Highlights•Sugar-binding C-type carbohydrate-recognition domains fall in five structural
groups.•Structures for many of these domains, covering all of the groups, have been …