Inline low-energy electron holography (LEEH) in conjunction with sample preparation by
electrospray ion beam deposition (ES-IBD) has recently emerged as a promising method for …

Crystallography has made a notable contribution to our knowledge of structural biology. For
traditional crystallography experiments, the growth of crystals with large size and high …

The European X-ray Free-Electron Laser (FEL) became the first operational high-repetition-
rate hard X-ray FEL with first lasing in May 2017. Biological structure determination has …

The emergence of high repetition-rate X-ray free-electron lasers (XFELs) powered by
superconducting accelerator technology enables the measurement of significantly more …

The reconstruction of a single-particle image from the modulus of its Fourier transform, by
phase-retrieval methods, has been extensively applied in X-ray structural science …

X-ray free electron lasers (XFELs) now routinely produce millijoule level pulses of x-ray
photons with tens of femtoseconds duration. Such x-ray intensities gave rise to the idea that …

As a critical component of coherent X-ray diffraction imaging (CDI), phase retrieval has been
extensively applied in X-ray structural science to recover the 3D morphological information …

Imaging of proteins at the single-molecule level can reveal conformational variability, which
is essential for the understanding of biomolecules. To this end, a biologically relevant state …

Single particle imaging at x-ray free electron lasers (XFELs) has the potential to determine
the structure and dynamics of single biomolecules at room temperature. Two major hurdles …

An outstanding question in X-ray single particle imaging experiments has been the
feasibility of imaging sub 10-nm-sized biomolecules under realistic experimental conditions …