The roles and implications of RNA m6A modification in cancer
Abstract N 6-Methyladenosine (m6A), the most prevalent internal modification in eukaryotic
mRNA, has been extensively and increasingly studied over the past decade. Dysregulation …
mRNA, has been extensively and increasingly studied over the past decade. Dysregulation …
N6-methyladenosine-mediated gene regulation and therapeutic implications
Abstract N6-methyladenosine (m 6 A) RNA methylation is the most abundant form of mRNA
modification in eukaryotes and is at the front line of biological and biomedical research. This …
modification in eukaryotes and is at the front line of biological and biomedical research. This …
N6-methyladenosine reader YTHDF family in biological processes: structures, roles, and mechanisms
L Chen, Y Gao, S Xu, J Yuan, M Wang, T Li… - Frontiers in …, 2023 - frontiersin.org
As the most abundant and conserved internal modification in eukaryote RNAs, N6-
methyladenosine (m6A) is involved in a wide range of physiological and pathological …
methyladenosine (m6A) is involved in a wide range of physiological and pathological …
The structure and function of YTHDF epitranscriptomic m6A readers
V Sikorski, S Selberg, M Lalowski, M Karelson… - Trends in …, 2023 - cell.com
Specific RNA sequences modified by a methylated adenosine, N 6-methyladenosine (m 6
A), contribute to the post-transcriptional regulation of gene expression. The quantity of m 6 A …
A), contribute to the post-transcriptional regulation of gene expression. The quantity of m 6 A …
N6-methyladenosine modification of circ_0003215 suppresses the pentose phosphate pathway and malignancy of colorectal cancer through the miR-663b/DLG4 …
B Chen, Y Hong, R Gui, H Zheng, S Tian, X Zhai… - Cell Death & …, 2022 - nature.com
Circular RNAs (circRNAs) are a recently discovered kind of regulatory RNAs that have
emerged as critical biomarkers of various types of cancers. Metabolic reprogramming has …
emerged as critical biomarkers of various types of cancers. Metabolic reprogramming has …
N6-methyladenosine modification—a key player in viral infection
X Zhang, Q Peng, L Wang - Cellular & Molecular Biology Letters, 2023 - Springer
Abstract N 6-methyladenosine (m6A) modification is a dynamic, reversible process and is
the most prevalent internal modification of RNA. This modification is regulated by three …
the most prevalent internal modification of RNA. This modification is regulated by three …
Epigenetic control of the Epstein-Barr lifecycle
R Guo, BE Gewurz - Current opinion in virology, 2022 - Elsevier
Epstein-Barr virus (EBV) infects 95% of adults worldwide, causes infectious mononucleosis,
is etiologically linked to multiple sclerosis and is associated with 200 000 cases of cancer …
is etiologically linked to multiple sclerosis and is associated with 200 000 cases of cancer …
RNA modification in cardiovascular disease: implications for therapeutic interventions
C Wang, X Hou, Q Guan, H Zhou, L Zhou… - … and Targeted Therapy, 2023 - nature.com
Cardiovascular disease (CVD) is the leading cause of death in the world, with a high
incidence and a youth-oriented tendency. RNA modification is ubiquitous and indispensable …
incidence and a youth-oriented tendency. RNA modification is ubiquitous and indispensable …
From A to m6A: The Emerging Viral Epitranscriptome
B Baquero-Perez, D Geers, J Díez - Viruses, 2021 - mdpi.com
There are over 100 different chemical RNA modifications, collectively known as the
epitranscriptome. N 6-methyladenosine (m6A) is the most commonly found internal RNA …
epitranscriptome. N 6-methyladenosine (m6A) is the most commonly found internal RNA …
Regulation of antiviral innate immunity by chemical modification of viral RNA
N Li, TM Rana - Wiley Interdisciplinary Reviews: RNA, 2022 - Wiley Online Library
More than 100 chemical modifications of RNA, termed the epitranscriptome, have been
described, most of which occur in prokaryotic and eukaryotic ribosomal, transfer, and …
described, most of which occur in prokaryotic and eukaryotic ribosomal, transfer, and …