Ultrasound contrast imaging: Fundamentals and emerging technology

H Yusefi, B Helfield - Frontiers in Physics, 2022 - frontiersin.org
The development of microbubble contrast agents has broadened the scope of medical
ultrasound imaging. Along with dedicated imaging techniques, these agents provide …

Performance benchmarking of microbubble-localization algorithms for ultrasound localization microscopy

B Heiles, A Chavignon, V Hingot, P Lopez… - Nature Biomedical …, 2022 - nature.com
Ultrafast ultrasound localization microscopy can be used to detect the subwavelength
acoustic scattering of intravenously injected microbubbles to obtain haemodynamic maps of …

[HTML][HTML] Super-resolution ultrasound microvascular imaging: Is it ready for clinical use?

P Song, JM Rubin, MR Lowerison - Zeitschrift für Medizinische Physik, 2023 - Elsevier
The field of super-resolution ultrasound microvascular imaging has been rapidly growing
over the past decade. By leveraging contrast microbubbles as point targets for localization …

3D transcranial ultrasound localization microscopy in the rat brain with a multiplexed matrix probe

A Chavignon, B Heiles, V Hingot… - IEEE Transactions …, 2021 - ieeexplore.ieee.org
Objective: Ultrasound Localization Microscopy (ULM) provides images of the
microcirculation in-depth in living tissue. However, its implementation in two-dimension is …

Aging-related cerebral microvascular changes visualized using ultrasound localization microscopy in the living mouse

MR Lowerison, NVC Sekaran, W Zhang, Z Dong… - Scientific reports, 2022 - nature.com
Aging-related cognitive decline is an emerging health crisis; however, no established
unifying mechanism has been identified for the cognitive impairments seen in an aging …

Super-resolution ultrasound localization microscopy based on a high frame-rate clinical ultrasound scanner: an in-human feasibility study

C Huang, W Zhang, P Gong, UW Lok… - Physics in Medicine …, 2021 - iopscience.iop.org
Non-invasive detection of microvascular alterations in deep tissues in vivo provides critical
information for clinical diagnosis and evaluation of a broad-spectrum of pathologies …

Super-resolution ultrasound through sparsity-based deconvolution and multi-feature tracking

J Yan, T Zhang, J Broughton-Venner… - IEEE transactions on …, 2022 - ieeexplore.ieee.org
Ultrasound super-resolution imaging through localisation and tracking of microbubbles can
achieve sub-wave-diffraction resolution in mapping both micro-vascular structure and flow …

A deep learning framework for spatiotemporal ultrasound localization microscopy

L Milecki, J Porée, H Belgharbi… - … on Medical Imaging, 2021 - ieeexplore.ieee.org
Ultrasound Localization Microscopy (ULM) can resolve the microvascular bed down to a few
micrometers. To achieve such performance, microbubble contrast agents must perfuse the …

[HTML][HTML] Non-invasive transcranial volumetric ultrasound localization microscopy of the rat brain with continuous, high volume-rate acquisition

JR McCall, F Santibanez, H Belgharbi, GF Pinton… - Theranostics, 2023 - ncbi.nlm.nih.gov
Rationale: Structure and function of the microvasculature provides critical information about
disease state, can be used to identify local regions of pathology, and has been shown to be …

Sensing ultrasound localization microscopy for the visualization of glomeruli in living rats and humans

L Denis, S Bodard, V Hingot, A Chavignon… - …, 2023 - thelancet.com
Background Estimation of glomerular function is necessary to diagnose kidney diseases.
However, the study of glomeruli in the clinic is currently done indirectly through urine and …