Uncovering the mechanisms of Acinetobacter baumannii virulence

CM Harding, SW Hennon, MF Feldman - Nature Reviews Microbiology, 2018 - nature.com
Acinetobacter baumannii is a nosocomial pathogen that causes ventilator-associated as
well as bloodstream infections in critically ill patients, and the spread of multidrug-resistant …

The structure and mechanism of the bacterial type II secretion system

S Naskar, M Hohl, M Tassinari… - Molecular …, 2021 - Wiley Online Library
The type II secretion system (T2SS) is a multi‐protein complex used by many bacteria to
move substrates across their cell membrane. Substrates released into the environment …

Urinary tract colonization is enhanced by a plasmid that regulates uropathogenic Acinetobacter baumannii chromosomal genes

G Di Venanzio, AL Flores-Mireles, JJ Calix… - Nature …, 2019 - nature.com
Multidrug resistant (MDR) Acinetobacter baumannii poses a growing threat to global health.
Research on Acinetobacter pathogenesis has primarily focused on pneumonia and …

Classification, structural biology, and applications of mucin domain-targeting proteases

DJ Shon, A Kuo, MJ Ferracane… - Biochemical …, 2021 - portlandpress.com
Epithelial surfaces throughout the body are coated by mucins, a class of proteins carrying
domains characterized by a high density of O-glycosylated serine and threonine residues …

Acinetobacter baumannii: Envelope Determinants That Control Drug Resistance, Virulence, and Surface Variability

E Geisinger, W Huo, J Hernandez-Bird… - Annual review of …, 2019 - annualreviews.org
Acinetobacter baumannii has emerged as an important nosocomial pathogen, particularly
for patients in intensive care units and with invasive indwelling devices. The most recent …

Pathogenicity and virulence of Acinetobacter baumannii: Factors contributing to the fitness in healthcare settings and the infected host

M Lucidi, D Visaggio, A Migliaccio, G Capecchi… - Virulence, 2024 - Taylor & Francis
Acinetobacter baumannii is a common cause of healthcare-associated infections and
hospital outbreaks, particularly in intensive care units. Much of the success of A. baumannii …

Architecture, function, and substrates of the type II secretion system

KV Korotkov, M Sandkvist - EcoSal Plus, 2019 - Am Soc Microbiol
The type II secretion system (T2SS) delivers toxins and a range of hydrolytic enzymes,
including proteases, lipases, and carbohydrate-active enzymes, to the cell surface or …

The Role of Antibiotic Resistant A. baumannii in the Pathogenesis of Urinary Tract Infection and the Potential of Its Treatment with the Use of Bacteriophage Therapy

N Bagińska, M Cieślik, A Górski, E Jończyk-Matysiak - Antibiotics, 2021 - mdpi.com
Acinetobacter baumannii are bacteria that belong to the critical priority group due to their
carbapenems and third generation cephalosporins resistance, which are last-chance …

Acinetobacter baumannii: Virulence Strategies and Host Defense Mechanisms

V Tiku - DNA and Cell Biology, 2022 - liebertpub.com
Acinetobacter baumannii is a highly antibiotic-resistant bacterial pathogen known to cause
severe life-threatening infections, including pneumonia, meningitis, and sepsis. Recent …

Uncovering the Secretion Systems of Acinetobacter baumannii: Structures and Functions in Pathogenicity and Antibiotic Resistance

P Li, S Zhang, J Wang, MM Al-Shamiri, B Han, Y Chen… - Antibiotics, 2023 - mdpi.com
Infections led by Acinetobacter baumannii strains are of great concern in healthcare
environments due to the strong ability of the bacteria to spread through different apparatuses …