Fast, high-resolution, non-destructive and quantitative characterization methods are needed
to develop materials with tailored properties at the nanoscale or to understand the …

Mechanical properties play important roles at different scales in biology. At the level of a
single cell, the mechanical properties mediate mechanosensing and mechanotransduction …

Visualization of biomedical samples in their native environments at the microscopic scale is
crucial for studying fundamental principles and discovering biomedical systems with …

The past two decades have seen atomic force microscopy (AFM) evolve from an
experimental technique to probe simple surface topography to one that can spatially map …

Mechanobiology aims to establish functional relationships between the mechanical state of
a living a cell and its physiology. The acquisition of force–distance curves with an AFM is by …

Cell aggregates, including sheets and spheroids, represent a simple yet powerful model
system to study both biochemical and biophysical intercellular interactions. However, it is …

Mechanical properties of living cells determined by cytoskeletal elements play a crucial role
in a wide range of biological functions. However, low-stress mapping of mechanical …

Cell transitions between the epithelial and mesenchymal phenotypes provide the regulated
morphogenesis and regeneration throughout the ontogenesis. The tissue mechanics and …

The viscoelastic parameters of the cell can report on the cell state, cellular processes and
diseases. Cell mechanics strongly rely on the properties of the cytoskeleton, an important …

Over the past several decades, atomic force microscopy (AFM) has advanced from a
technique used primarily for surface topography imaging to one capable of characterizing a …