[HTML][HTML] H2O2 is an important mediator of UVB-induced EGF-receptor phosphorylation in cultured keratinocytes
Exposure of human keratinocytes to physiologic doses of ultraviolet B (UVB) radiation
induces phosphorylation of the epidermal growth factor receptor (EGFR). We demonstrate …
induces phosphorylation of the epidermal growth factor receptor (EGFR). We demonstrate …
Characterization and expression of novel 60‐kDa and 110‐kDa EGFR isoforms in human placenta
JL Reiter, NJ Maihle - Annals of the New York Academy of …, 2003 - Wiley Online Library
The epidermal growth factor receptor (EGFR) and related family members (ERBB2, ERBB3,
and ERBB4) previously have been shown to play pivotal roles in the development of female …
and ERBB4) previously have been shown to play pivotal roles in the development of female …
Domain-level antibody epitope mapping through yeast surface display of epidermal growth factor receptor fragments
Individual domains from extracellular proteins are potential reagents for biochemical
characterization of ligand/receptor interactions and antibody binding sites. Here, we …
characterization of ligand/receptor interactions and antibody binding sites. Here, we …
Soluble epidermal growth factor receptor (sEGFR/sErbB1) as a potential risk, screening, and diagnostic serum biomarker of epithelial ovarian cancer
AT Baron, EM Cora, JM Lafky, CH Boardman… - … Biomarkers & Prevention, 2003 - AACR
Epithelial ovarian cancer (EOC) is the leading cause of death from gynecologic
malignancies in the United States, for which risk assessment, screening, and diagnostic …
malignancies in the United States, for which risk assessment, screening, and diagnostic …
EGFR isoforms and gene regulation in human endometrial cancer cells
L Albitar, G Pickett, M Morgan, JA Wilken, NJ Maihle… - Molecular cancer, 2010 - Springer
Background Epidermal growth factor (EGF) and its receptor (EGFR) constitute a principal
growth-promoting pathway in endometrial cancer cells. Pre-clinical studies were undertaken …
growth-promoting pathway in endometrial cancer cells. Pre-clinical studies were undertaken …
Serum sErbB1 and epidermal growth factor levels as tumor biomarkers in women with stage III or IV epithelial ovarian cancer
AT Baron, JM Lafky, CH Boardman… - … Biomarkers & Prevention, 1999 - AACR
Epithelial ovarian cancer (EOC) has a high mortality rate, which is due primarily to the fact
that early clinical symptoms are vague and nonspecific; hence, this disease often goes …
that early clinical symptoms are vague and nonspecific; hence, this disease often goes …
Shedding of epidermal growth factor receptor is a regulated process that occurs with overexpression in malignant cells
M Perez-Torres, BL Valle, NJ Maihle… - Experimental cell …, 2008 - Elsevier
Soluble isoforms of the epidermal growth factor receptor (sEGFR) previously have been
identified in the conditioned culture media (CCM) of the vulvar adenocarcinoma cell line …
identified in the conditioned culture media (CCM) of the vulvar adenocarcinoma cell line …
Directed evolution of the epidermal growth factor receptor extracellular domain for expression in yeast
YS Kim, R Bhandari, JR Cochran… - PROTEINS …, 2006 - Wiley Online Library
The extracellular domain of epidermal growth factor receptor (EGFR‐ECD) has been
engineered through directed evolution and yeast surface display using conformationally …
engineered through directed evolution and yeast surface display using conformationally …
[HTML][HTML] Expression of EGFR isoform D is regulated by HER receptor activators in breast cancer cells
L Negrón-Vega, EM Cora, M Pérez-Torres… - … and biophysics reports, 2022 - Elsevier
Human epidermal growth factor receptor isoform D (EGFR; isoform D) is a soluble protein
from a 3 kb alternate mRNA transcript that arises from the human EGFR gene. Several …
from a 3 kb alternate mRNA transcript that arises from the human EGFR gene. Several …
[HTML][HTML] Extracellular domain shedding influences specific tumor uptake and organ distribution of the EGFR PET tracer 89Zr-imgatuzumab
M Pool, A Kol, MN Lub-de Hooge, CA Gerdes… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Preclinical positron emission tomography (PET) imaging revealed a mismatch between in
vivo epidermal growth factor receptor (EGFR) expression and EGFR antibody tracer tumor …
vivo epidermal growth factor receptor (EGFR) expression and EGFR antibody tracer tumor …