[HTML][HTML] Gap junctions
Gap junctions are essential to the function of multicellular animals, which require a high
degree of coordination between cells. In vertebrates, gap junctions comprise connexins and …
degree of coordination between cells. In vertebrates, gap junctions comprise connexins and …
Drug therapies and delivery mechanisms to treat perturbed skin wound healing
Acute wound healing is an orderly process of four overlapping events: haemostasis,
inflammation, proliferation and remodelling. A drug delivery system with a temporal control …
inflammation, proliferation and remodelling. A drug delivery system with a temporal control …
A cold plasma jet accelerates wound healing in a murine model of full‐thickness skin wounds
Cold plasma has been successfully applied in several fields of medicine that require, for
example, pathogen inactivation, implant functionalization or alteration of cellular activity …
example, pathogen inactivation, implant functionalization or alteration of cellular activity …
Inhibitors of connexin and pannexin channels as potential therapeutics
J Willebrords, M Maes, SC Yanguas… - Pharmacology & …, 2017 - Elsevier
While gap junctions support the exchange of a number of molecules between neighboring
cells, connexin hemichannels provide communication between the cytosol and the …
cells, connexin hemichannels provide communication between the cytosol and the …
Selective inhibition of Cx43 hemichannels by Gap19 and its impact on myocardial ischemia/reperfusion injury
N Wang, E De Vuyst, R Ponsaerts, K Boengler… - Basic research in …, 2013 - Springer
Abstract Connexin-43 (Cx43), a predominant cardiac connexin, forms gap junctions (GJs)
that facilitate electrical cell–cell coupling and unapposed/nonjunctional hemichannels that …
that facilitate electrical cell–cell coupling and unapposed/nonjunctional hemichannels that …
Biological role of connexin intercellular channels and hemichannels
R Kar, N Batra, MA Riquelme, JX Jiang - Archives of biochemistry and …, 2012 - Elsevier
Gap junctions (GJ) and hemichannels (HC) formed from the protein subunits called
connexins are transmembrane conduits for the exchange of small molecules and ions …
connexins are transmembrane conduits for the exchange of small molecules and ions …
Adipose‐derived mesenchymal stem cells and regenerative medicine
M Konno, A Hamabe, S Hasegawa… - Development …, 2013 - Wiley Online Library
Adipose tissue‐derived mesenchymal stem cells (ADSC s) are multipotent and can
differentiate into various cell types, including osteocytes, adipocytes, neural cells, vascular …
differentiate into various cell types, including osteocytes, adipocytes, neural cells, vascular …
Connexins and their channels in inflammation
J Willebrords, S Crespo Yanguas, M Maes… - Critical reviews in …, 2016 - Taylor & Francis
Inflammation may be caused by a variety of factors and is a hallmark of a plethora of acute
and chronic diseases. The purpose of inflammation is to eliminate the initial cell injury …
and chronic diseases. The purpose of inflammation is to eliminate the initial cell injury …
Glial connexins and pannexins in the healthy and diseased brain
C Giaume, CC Naus, JC Sáez… - Physiological …, 2021 - journals.physiology.org
Over the past several decades a large amount of data have established that glial cells, the
main cell population in the brain, dynamically interact with neurons and thus impact their …
main cell population in the brain, dynamically interact with neurons and thus impact their …
Connexin mimetic peptides inhibit Cx43 hemichannel opening triggered by voltage and intracellular Ca2+ elevation
N Wang, M De Bock, G Antoons, AK Gadicherla… - Basic research in …, 2012 - Springer
Connexin mimetic peptides (CxMPs), such as Gap26 and Gap27, are known as inhibitors of
gap junction channels but evidence is accruing that these peptides also inhibit …
gap junction channels but evidence is accruing that these peptides also inhibit …