Lassa fever—the road ahead
RF Garry - Nature Reviews Microbiology, 2023 - nature.com
Lassa virus (LASV) is endemic in the rodent populations of Sierra Leone, Nigeria and other
countries in West Africa. Spillover to humans occurs frequently and results in Lassa fever, a …
countries in West Africa. Spillover to humans occurs frequently and results in Lassa fever, a …
[HTML][HTML] Ribavirin for the treatment of Lassa fever: A systematic review and meta-analysis
KA Eberhardt, J Mischlinger, S Jordan, M Groger… - International Journal of …, 2019 - Elsevier
Objectives Lassa fever (LF) causes annual outbreaks in endemic regions with high mortality
of symptomatic patients. Ribavirin is recommended as standard treatment for LF in national …
of symptomatic patients. Ribavirin is recommended as standard treatment for LF in national …
Genomic analysis of Lassa virus during an increase in cases in Nigeria in 2018
During 2018, an unusual increase in Lassa fever cases occurred in Nigeria, raising concern
among national and international public health agencies. We analyzed 220 Lassa virus …
among national and international public health agencies. We analyzed 220 Lassa virus …
Systematic analysis of infectious disease outcomes by age shows lowest severity in school-age children
The COVID-19 pandemic has ignited interest in age-specific manifestations of infection but
surprisingly little is known about relative severity of infectious disease between the extremes …
surprisingly little is known about relative severity of infectious disease between the extremes …
Metagenomic surveillance uncovers diverse and novel viral taxa in febrile patients from Nigeria
Effective infectious disease surveillance in high-risk regions is critical for clinical care and
pandemic preemption; however, few clinical diagnostics are available for the wide range of …
pandemic preemption; however, few clinical diagnostics are available for the wide range of …
Lassa fever: epidemiology, clinical features, diagnosis, management and prevention
Lassa fever, is an acute zoonotic disease of humans that is mainly endemic to West African
countries of Guinea, Liberia, Nigeria, and Sierra Leone. 1–3 Other countries such as Mali …
countries of Guinea, Liberia, Nigeria, and Sierra Leone. 1–3 Other countries such as Mali …
Genome-wide association study identifies human genetic variants associated with fatal outcome from Lassa fever
Infection with Lassa virus (LASV) can cause Lassa fever, a haemorrhagic illness with an
estimated fatality rate of 29.7%, but causes no or mild symptoms in many individuals. Here …
estimated fatality rate of 29.7%, but causes no or mild symptoms in many individuals. Here …
[HTML][HTML] Epidemiologic and clinical features of Lassa fever outbreak in Nigeria, January 1–May 6, 2018
EA Ilori, Y Furuse, OB Ipadeola… - Emerging infectious …, 2019 - ncbi.nlm.nih.gov
SYNOPSIS State), or the National Reference Laboratory (Federal Capital Territory).
Laboratory confirmation was performed by using RT-PCR by means of the RealStar Lassa …
Laboratory confirmation was performed by using RT-PCR by means of the RealStar Lassa …
A human monoclonal antibody combination rescues nonhuman primates from advanced disease caused by the major lineages of Lassa virus
RW Cross, ML Heinrich, KA Fenton… - Proceedings of the …, 2023 - National Acad Sciences
There are no approved treatments for Lassa fever (LF), which is responsible for thousands of
deaths each year in West Africa. A major challenge in developing effective medical …
deaths each year in West Africa. A major challenge in developing effective medical …
[HTML][HTML] Using autopsies to dissect COVID-19 pathogenesis
The emergence of SARS-CoV-2 has resulted in millions of deaths as a result of COVID-19.
Suitable models were missing at the beginning of the pandemic, and studies investigating …
Suitable models were missing at the beginning of the pandemic, and studies investigating …