Black Cumin (Nigella sativa L.): A Comprehensive Review on Phytochemistry, Health Benefits, Molecular Pharmacology, and Safety

MA Hannan, MA Rahman, AAM Sohag, MJ Uddin… - Nutrients, 2021 - mdpi.com
Mounting evidence support the potential benefits of functional foods or nutraceuticals for
human health and diseases. Black cumin (Nigella sativa L.), a highly valued nutraceutical …

Role of oxidative stress in alcohol-induced liver injury

AI Cederbaum, Y Lu, D Wu - Archives of toxicology, 2009 - Springer
Reactive oxygen species (ROS) are highly reactive molecules that are naturally generated
in small amounts during the body's metabolic reactions and can react with and damage …

[PDF][PDF] Alcohol and oxidative liver injury

A Dey, AI Cederbaum - Hepatology, 2006 - Wiley Online Library
Acute and chronic ethanol treatment has been shown to increase the production of reactive
oxygen species, lower cellular antioxidant levels, and enhance oxidative stress in many …

Oxidants and antioxidants in alcohol-induced liver disease

GE Arteel - Gastroenterology, 2003 - Elsevier
Although there are numerous experimental data indicating that oxidative stress plays a role
in the initiation and progression of alcohol-induced liver disease (ALD), this work has yet to …

Oxidative stress and alcoholic liver disease

D Wu, AI Cederbaum - Seminars in liver disease, 2009 - thieme-connect.com
Reactive oxygen species (ROS) are highly reactive molecules that are naturally generated
in small amounts during the body's metabolic reactions and can react with and damage …

Oxidative stress and enzymatic antioxidant status in patients with nonalcoholic steatohepatitis

M Koruk, S Taysi, MC Savas, O Yilmaz… - Annals of Clinical & …, 2004 - Assoc Clin Scientists
Oxidative stress is an important pathophysiological mechanism in nonalcoholic
steatohepatitis (NASH). To assess whether there are relationships between oxidative stress …

Recent advances on the roles of NO in cancer and chronic inflammatory disorders

JR Kanwar, RK Kanwar, H Burrow… - Current medicinal …, 2009 - ingentaconnect.com
Nitric oxide (NO) is a short-life molecule produced by the enzyme known as the nitric oxide
synthase (NOS), in a reaction that converts arginine and oxygen into citrulline and NO …

Mechanisms and cell signaling in alcoholic liver disease

JI Beier, CJ McClain - 2010 - degruyter.com
Alcoholic liver disease (ALD) remains a major cause of morbidity and mortality worldwide.
For example, the Veterans Administration Cooperative Studies reported that patients with …

[PDF][PDF] The contemporary role of antioxidant therapy in attenuating liver ischemia‐reperfusion injury: A review

GK Glantzounis, HJ Salacinski, W Yang… - Liver …, 2005 - Wiley Online Library
Oxidative stress is an important factor in many pathological conditions such as inflammation,
cancer, ageing and organ response to ischemia‐reperfusion. Humans have developed a …

In vivo imaging of hepatocellular nitric oxide using a hepatocyte-targeting fluorescent sensor

P Zhang, Y Tian, H Liu, J Ren, H Wang… - Chemical …, 2018 - pubs.rsc.org
Imaging of hepatocellular nitric oxide (NO) in vivo is of great importance for understanding
its roles in liver diseases, but such an imaging approach is still lacking. Herein, a hepatocyte …