This narrative state-of-the-art review paper describes the progress in the understanding and
treatment of Posttraumatic Stress Disorder (PTSD). Over the last four decades, the scientific …

Genome-wide association studies (GWAS) provide biological insights into disease onset
and progression and have potential to produce clinically useful biomarkers. A growing body …

Post-traumatic stress disorder (PTSD) genetics are characterized by lower discoverability
than most other psychiatric disorders. The contribution to biological understanding from …

Importance Posttraumatic stress disorder (PTSD) has been reported to be a risk factor for
several physical and somatic symptoms. However, the genetics of PTSD and its potential …

Objective: Multidisciplinary studies of posttraumatic stress disorder (PTSD) and major
depressive disorder (MDD) implicate the dorsolateral prefrontal cortex (DLPFC) in disease …

Background Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interaction
frequently accompanied by mental conditions, including depression and anxiety. Despite …

Thinness and anorexia nervosa are both characterised by persistent low weight. Individuals
with anorexia nervosa concurrently report distorted perceptions of their body and engage in …

The internalizing spectrum encompasses a subset of psychopathologies characterized by
emotional liability, anhedonia, anxiousness, distress, and fear, and includes, among others …

Determining whether the RNA isoforms from medically relevant genes have distinct
functions could facilitate direct targeting of RNA isoforms for disease treatment. Here, as a …

Due to alternative splicing, human protein-coding genes average over eight RNA isoforms,
resulting in nearly four distinct protein coding sequences per gene. Long-read RNAseq …