The periconceptional period, reproduction and long-term health of offspring: the importance of one-carbon metabolism

RPM Steegers-Theunissen, J Twigt… - Human reproduction …, 2013 - academic.oup.com
BACKGROUND Most reproductive failures originate during the periconceptional period and
are influenced by the age and the lifestyle of parents-to-be. We advance the hypothesis that …

Environmental exposures and congenital heart disease

R Boyd, H McMullen, H Beqaj, D Kalfa - Pediatrics, 2022 - publications.aap.org
Congenital heart disease (CHD) is the most common congenital abnormality worldwide,
affecting 8 to 12 infants per 1000 births globally and causing> 40% of prenatal deaths …

Periconceptional Maternal Folic Acid Use of 400 µg per Day Is Related to Increased Methylation of the IGF2 Gene in the Very Young Child

RP Steegers-Theunissen, SA Obermann-Borst… - PloS one, 2009 - journals.plos.org
Background Countries worldwide recommend women planning pregnancy to use daily 400
µg of synthetic folic acid in the periconceptional period to prevent birth defects in children …

[HTML][HTML] Vitamin B-12 and perinatal health

JL Finkelstein, AJ Layden, PJ Stover - Advances in Nutrition, 2015 - Elsevier
ABSTRACT Vitamin B-12 deficiency (< 148 pmol/L) is associated with adverse maternal and
neonatal outcomes, including developmental anomalies, spontaneous abortions …

Environmental risk factors for congenital heart disease

JI Kalisch-Smith, N Ved… - Cold Spring Harbor …, 2020 - cshperspectives.cshlp.org
Congenital heart disease (CHD) has many forms and a wide range of causes. Clinically, it is
important to understand the causes. This allows estimation of recurrence rate, guides …

[图书][B] Folate in health and disease

LB Bailey - 2009 - taylorfrancis.com
During the fifteen years since the bestselling first edition of Folate in Health and Disease
was published, there have been thousands of new research studies related to folate and its …

Vitamin D and metabolic disturbances in polycystic ovary syndrome (PCOS): A cross-sectional study

YHM Krul-Poel, PP Koenders… - PloS one, 2018 - journals.plos.org
Objective To compare vitamin D status in women with PCOS versus fertile women and
subsequently evaluate the association between vitamin D status and metabolic disturbances …

A more atherogenic serum lipoprotein profile is present in women with polycystic ovary syndrome: a case-control study

O Valkenburg… - The Journal of …, 2008 - academic.oup.com
Context: Polycystic ovary syndrome (PCOS) is associated with a higher frequency of
cardiovascular risk factors. Apolipoprotein (apo) AI and apoB are potent markers for …

Site specificity of aneurysmal disease

PE Norman, JT Powell - Circulation, 2010 - Am Heart Assoc
Aneurysms are localized pathological dilations of any vessel, and in arteries, a diameter of
1.5 times that of the normal artery is a generally accepted definition. Morphologically …

An artificial neural network prediction model of congenital heart disease based on risk factors: A hospital-based case-control study

H Li, M Luo, J Zheng, J Luo, R Zeng, N Feng, Q Du… - Medicine, 2017 - journals.lww.com
An artificial neural network prediction model of congenital... : Medicine An artificial neural
network prediction model of congenital heart disease based on risk factors: A hospital-based …