Revisiting diagnosis and treatment of hypertrophic cardiomyopathy: current practice and novel perspectives

A Ottaviani, D Mansour, LV Molinari, K Galanti… - Journal of Clinical …, 2023 - mdpi.com
Sarcomeric hypertrophic cardiomyopathy (HCM) is a prevalent genetic disorder
characterised by left ventricular hypertrophy, myocardial disarray, and an increased risk of …

Aficamten: a breakthrough therapy for symptomatic obstructive hypertrophic cardiomyopathy

SA Sebastian, I Padda, EJ Lehr, G Johal - American Journal of …, 2023 - Springer
Aficamten is a novel cardiac myosin inhibitor that has demonstrated its ability to safely lower
left ventricular outflow tract (LVOT) gradients and improve heart failure symptoms in patients …

Krüpple-like factors in cardiomyopathy: emerging player and therapeutic opportunities

LK Gui, HJ Liu, LJ Jin, XC Peng - Frontiers in Cardiovascular Medicine, 2024 - frontiersin.org
Cardiomyopathy, a heterogeneous pathological condition characterized by changes in
cardiac structure or function, represents a significant risk factor for the prevalence and …

[HTML][HTML] Integrated bioinformatics and experiment revealed that cuproptosis is the potential common pathogenesis of three kinds of primary cardiomyopathy

M Wang, X Xu, J Li, Z Gao, Y Ding, X Chen… - Aging (Albany …, 2023 - ncbi.nlm.nih.gov
Cuproptosis is a recently reported new mode of programmed cell death which might be a
potential co-pathogenesis of three kinds of primary cardiomyopathy. However, no …

[HTML][HTML] Sex disparities in the use and outcomes of septal reduction therapies for obstructive hypertrophic cardiomyopathy

C Diaz-Arocutipa, G Moreno, M Giráldez… - CJC Open, 2024 - Elsevier
Background There is limited data examining potential sex-based disparities in the utilization
and complications of septal reduction therapy (SRT) in patients with obstructive hypertrophic …

A Novel Truncating Variant in MYBPC3 Causes Hypertrophic Cardiomyopathy

Y Zhang, W Gong, Y Cong, X Zhang, Z Zheng - medRxiv, 2024 - medrxiv.org
Background Familial hypertrophic cardiomyopathy (HCM) is the most common genetic
cardiovascular disease. Related mutations contributing to hypercontractility and poor …

[HTML][HTML] 当心脏遇上射线: 立体定向放射治疗用于治疗肥厚型梗阻性心肌病的前景

廖礼义, 汤瀚泽, 胡琳, 周胜华… - Journal of Central South …, 2023 - ncbi.nlm.nih.gov
肥厚型梗阻性心肌病(hypertrophic obstructive cardiomyopathy, HOCM)
是一种以心室间隔肥厚和左心室流出道梗阻为主要特征的遗传性心脏疾病 …

Hypertension and its association to phenotype on left ventricular function in hypertrophic cardiomyopathy patients assessed by cardiovascular magnetic resonance …

Z Yang, T Zhang, F Yao, M Wen, Z Wang, X Meng… - Clinical Radiology, 2024 - Elsevier
Aim The impact of hypertension (HT) on phenotypic expression in individuals with
hypertrophic cardiomyopathy (HCM) is unclear. Materials and methods Thirty-six HCM …

[HTML][HTML] Clinical Effect of the Modified Morrow Septal Myectomy Procedure for Biventricular Hypertrophic Cardiomyopathy

T Tan, W Zhu, J Ma, B Fu, X Zeng, R Wang… - Reviews in …, 2024 - imrpress.com
Background: Right ventricular involvement in hypertrophic cardiomyopathy is uncommon.
This study aimed to evaluate clinical outcomes of the modified septal myectomy in patients …

When radiation meets the heart: Future of stereotactic body radiation therapy for hypertrophic obstructive cardiomyopathy.

L Liao, H Tang, L Hu, S Zhou, X Li - Zhong nan da xue xue bao. Yi …, 2023 - europepmc.org
肥厚型梗阻性心肌病 (hypertrophic obstructive cardiomyopathy, HOCM)
是一种以心室间隔肥厚和左心室流出道梗阻为主要特征的遗传性心脏疾病. 传统的治疗方法 …