The devastating clinical consequences of child abuse and neglect: increased disease vulnerability and poor treatment response in mood disorders

ETC Lippard, CB Nemeroff - American journal of psychiatry, 2020 - Am Psychiatric Assoc
A large body of evidence has demonstrated that exposure to childhood maltreatment at any
stage of development can have long-lasting consequences. It is associated with a marked …

Emotion regulation as mediator between childhood adversity and psychopathology: A meta-analysis

AC Miu, A Szentágotai-Tătar, R Balazsi… - Clinical psychology …, 2022 - Elsevier
Childhood adversity is a major risk factor for multiple forms of psychopathology, and recent
efforts have focused on understanding the underlying psychological mechanisms. One …

Child maltreatment and the development of psychopathology: The role of developmental timing and chronicity

J Russotti, JM Warmingham, EB Duprey… - Child abuse & …, 2021 - Elsevier
Background The effects of child maltreatment (CM) on psychopathology are well-
established, yet the complex effects of timing and chronicity of maltreatment exposure on the …

Early life stress alters transcriptomic patterning across reward circuitry in male and female mice

CJ Peña, M Smith, A Ramakrishnan, HM Cates… - Nature …, 2019 - nature.com
Abuse, neglect, and other forms of early life stress (ELS) significantly increase risk for
psychiatric disorders including depression. In this study, we show that ELS in a postnatal …

Inflammation and early life stress: An updated review of childhood trauma and inflammatory markers in adulthood

M Brown, C Worrell, CM Pariante - Pharmacology Biochemistry and …, 2021 - Elsevier
Inflammation, as a neurobiological consequence of childhood trauma, has frequently been
reported across research, however, recent investigations suggest this relationship may be …

Reactivation of early-life stress-sensitive neuronal ensembles contributes to lifelong stress hypersensitivity

JA Balouek, CA Mclain, AR Minerva… - Journal of …, 2023 - Soc Neuroscience
Early-life stress (ELS) is one of the strongest lifetime risk factors for depression, anxiety,
suicide, and other psychiatric disorders, particularly after facing additional stressful events …

Emotional dysregulation mediates the impact of childhood trauma on psychological distress: First Italian data during the early phase of COVID-19 outbreak

D Janiri, L Moccia, L Dattoli, M Pepe… - Australian & New …, 2021 - journals.sagepub.com
Background: The coronavirus disease 2019 pandemic represents an unprecedented
traumatic stressor to mental health. Psychological distress is considered a reliable proxy for …

The dimensionality of adverse childhood experiences: a scoping review of ACE dimensions measurement

LM Krinner, J Warren-Findlow, J Bowling, LM Issel… - Child Abuse & …, 2021 - Elsevier
Objective Despite extensive research, the concept of adverse childhood experiences (ACEs)
is not fully developed and there is low agreement on how the concept should be defined and …

The timing effect of childhood maltreatment in depression: A systematic review and meta-analysis

M Li, T Gao, Y Su, Y Zhang, G Yang… - Trauma, Violence, & …, 2023 - journals.sagepub.com
Although empirical evidence has confirmed the causal relationship between childhood
maltreatment and depression, findings are inconsistent on the magnitude of the effect of age …

A 1‐year follow‐up study of the longitudinal interplay between emotion dysregulation and childhood trauma in the treatment of anorexia nervosa

E Cassioli, E Rossi, G D'Anna, M Martelli… - … Journal of Eating …, 2022 - Wiley Online Library
Objective The study aimed to investigate the complex relationship between eating disorder
(ED) specific psychopathology, emotion dysregulation, and their longitudinal variations in …