Use of metatranscriptomics in microbiome research

S Bashiardes… - … and biology insights, 2016 - journals.sagepub.com
The human intestinal microbiome is a microbial ecosystem that expresses as many as 100
times more genes than the human host, thereby constituting an important component of the …

cis-Antisense RNA, Another Level of Gene Regulation in Bacteria

J Georg, WR Hess - Microbiology and Molecular Biology Reviews, 2011 - Am Soc Microbiol
SUMMARY A substantial amount of antisense transcription is a hallmark of gene expression
in eukaryotes. However, antisense transcription was first demonstrated in bacteria almost 50 …

Rfam 14: expanded coverage of metagenomic, viral and microRNA families

I Kalvari, EP Nawrocki… - Nucleic Acids …, 2021 - academic.oup.com
Rfam is a database of RNA families where each of the 3444 families is represented by a
multiple sequence alignment of known RNA sequences and a covariance model that can be …

Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions

U Mäder, P Nicolas, M Depke, J Pané-Farré… - PLoS …, 2016 - journals.plos.org
Staphylococcus aureus is a major pathogen that colonizes about 20% of the human
population. Intriguingly, this Gram-positive bacterium can survive and thrive under a wide …

Genome-wide antisense transcription drives mRNA processing in bacteria

I Lasa, A Toledo-Arana, A Dobin… - Proceedings of the …, 2011 - National Acad Sciences
RNA deep sequencing technologies are revealing unexpected levels of complexity in
bacterial transcriptomes with the discovery of abundant noncoding RNAs, antisense RNAs …

RNA-mediated regulation in pathogenic bacteria

I Caldelari, Y Chao, P Romby… - Cold Spring …, 2013 - perspectivesinmedicine.cshlp.org
Pathogenic bacteria possess intricate regulatory networks that temporally control the
production of virulence factors, and enable the bacteria to survive and proliferate after host …

RNase III CLASH in MRSA uncovers sRNA regulatory networks coupling metabolism to toxin expression

SW McKellar, I Ivanova, P Arede, RL Zapf… - Nature …, 2022 - nature.com
Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial pathogen responsible for
significant human morbidity and mortality. Post-transcriptional regulation by small RNAs …

RNAs: regulators of bacterial virulence

J Gripenland, S Netterling, E Loh, T Tiensuu… - Nature Reviews …, 2010 - nature.com
RNA-based pathways that regulate protein expression are much more widespread than
previously thought. Regulatory RNAs, including 5′ and 3′ untranslated regions next to the …

Genome-wide screen for genes involved in eDNA release during biofilm formation by Staphylococcus aureus

AS DeFrancesco, N Masloboeva… - Proceedings of the …, 2017 - National Acad Sciences
Staphylococcus aureus is a leading cause of both nosocomial and community-acquired
infection. Biofilm formation at the site of infection reduces antimicrobial susceptibility and can …

Broadening the definition of bacterial small RNAs: characteristics and mechanisms of action

MC Carrier, D Lalaouna, E Massé - Annual review of …, 2018 - annualreviews.org
The first report of trans-acting RNA-based regulation in bacterial cells dates back to 1984.
Subsequent studies in diverse bacteria unraveled shared properties of trans-acting small …