An innovative strategy for Gefitinib quantification in pharmaceutical and plasma samples using a graphene quantum dots-combined gold nanoparticles composite …

J Cao, Y Shi, J Chen, Z Yan, M Zhang, M Jin, L Shui… - Microchimica Acta, 2024 - Springer
An innovative methodology is proposed for quantifying Gefitinib (GFT) using an
electrochemical sensor constructed from a composite of graphene quantum dots (GQDs) …

Two stability indicating chromatographic methods: TLC densitometric versus HPLC method for the simultaneous determination of brinzolamide and timolol maleate in …

AA Mandour, N Nabil, HE Zaazaa, MM Ibrahim… - Separations, 2023 - mdpi.com
A comparative study between two stability-indicating chromatographic methods for the assay
of brinzolamide and timolol maleate in the co-existence of the probable carcinogenic …

Amelioration of the therapeutic potential of gefitinib against breast cancer using nanostructured lipid carriers

P Kumar, B Mangla, S Javed, W Ahsan… - Nanomedicine, 2023 - Taylor & Francis
Aim: This study aimed to improve the delivery and therapeutic potential of gefitinib (GTB)
against breast cancer by preparing GTB-loaded, nanostructured lipid carriers (GTB-NLCs) …

Facile synthesis of nitrogen-doped carbon dots for ultrasensitive detection of anticancer drug gefitinib based on IFE

Y He, H Wang, Y Yan, X Jiang, H Zou… - Spectrochimica Acta Part A …, 2024 - Elsevier
Gefitinib, a highly significant antitumor drug, is now commonly employed in clinical settings
as a first-line treatment for patients with advanced or metastatic non-small cell lung cancer …

Synergistic Phototherapy-Molecular Targeted Therapy Combined with Tumor Exosome Nanoparticles for Oral Squamous Cell Carcinoma Treatment

M Li, S Yin, A Xu, L Kang, Z Ma, F Liu, T Yang, P Sun… - Pharmaceutics, 2023 - mdpi.com
Oral squamous cell carcinoma (OSCC) contributes to more than 90% of all oral
malignancies, yet the performance of traditional treatments is impeded by limited therapeutic …

Solid Dispersions of Gefitinib with D-α-Tocopherol Polyethylene Glycol-1000 Succinate and 2-Hydroxypropyl β-Cyclodextrin Complex Improved Their Solubility …

MA Kalam, AA Alhowyan, SS Alhudaithi, MS Khan… - Applied Sciences, 2023 - mdpi.com
This study focuses on the development and characterization of solid dispersions (SDs) of
Gefitinib (GEF) to improve its aqueous solubility and therapeutic activity against lung cancer …

Development of an Analytical Quality by Design RP-HPLC Method and Its Validation for Estimation of Gefitinib From Bulk, Tablet Dosage Form, and Complex …

MP More, SR Pardeshi, R Tade… - Journal of AOAC …, 2024 - academic.oup.com
Background Estimation of the drug and development of the method is a critical aspect of
formulation development and a critical factor for analytical scientists. Gefitinib is a poorly …