[HTML][HTML] Plant-based sterols and stanols in health & disease:“Consequences of human development in a plant-based environment?”

J Plat, S Baumgartner, T Vanmierlo, D Lütjohann… - Progress in lipid …, 2019 - Elsevier
Dietary plant sterols and stanols as present in our diet and in functional foods are well-
known for their inhibitory effects on intestinal cholesterol absorption, which translates into …

Phytosterols and their derivatives: Potential health‐promoting uses against lipid metabolism and associated diseases, mechanism, and safety issues

S Feng, T Belwal, L Li, J Limwachiranon… - … Reviews in Food …, 2020 - Wiley Online Library
Consumption of phytosterols (PSs), the plant‐based analogs of cholesterol, can reduce
serum cholesterol levels. This review discusses the current state of the art into the research …

Phytosterols and cardiovascular disease

U Makhmudova, PC Schulze, D Lütjohann… - Current atherosclerosis …, 2021 - Springer
Abstract Purpose of Review Coronary heart disease is the leading cause of mortality
worldwide. Elevated blood cholesterol levels are not only the major but also the best …

Current knowledge on the mechanism of atherosclerosis and pro-atherosclerotic properties of oxysterols

A Zmysłowski, A Szterk - Lipids in health and disease, 2017 - Springer
Due to the fact that one of the main causes of worldwide deaths are directly related to
atherosclerosis, scientists are constantly looking for atherosclerotic factors, in an attempt to …

Implementing phytosterols into medical practice as a cholesterol-lowering strategy: overview of efficacy, effectiveness, and safety

SS AbuMweis, CPF Marinangeli, J Frohlich… - Canadian Journal of …, 2014 - Elsevier
More than 200 clinical trial reports and several meta-analyses have demonstrated that
phytosterols (PSs), natural components of plants, induce clinically relevant reductions in …

Molecular insights into the mechanisms underlying the cholesterol-lowering effects of phytosterols

L Cedó, M Farràs, M Lee-Rueckert… - Current medicinal …, 2019 - ingentaconnect.com
Dietary phytosterols, which comprise plant sterols and stanols, reduce plasma Low-Density
Lipoprotein-Cholesterol (LDL-C) levels when given 2 g/day. Since this dose has not been …

The lipid-lowering effects and associated mechanisms of dietary phytosterol supplementation

JH Dumolt, TC Rideout - Current pharmaceutical design, 2017 - ingentaconnect.com
Phytosterols (PS) are plant-based structural analogous of mammalian cholesterol that have
been shown to lower blood cholesterol concentrations by~ 10%, although inter-individual …

Linking phytosterols and oxyphytosterols from food to brain health: origins, effects, and underlying mechanisms

F Jie, X Yang, L Wu, M Wang, B Lu - Critical reviews in food …, 2022 - Taylor & Francis
Phytosterols and their oxidation products, namely oxyphytosterols, are natural compounds
present in plant foods. With increased intake of phytosterol-enriched functional food …

Plant sterols and plant stanols in cholesterol management and cardiovascular prevention

F Barkas, E Bathrellou, T Nomikos, D Panagiotakos… - Nutrients, 2023 - mdpi.com
Atherosclerotic cardiovascular disease (ASCVD) remains the major mortality cause in
developed countries with hypercholesterolaemia being one of the primary modifiable …

Phytosterol oxidation products in enriched foods: Occurrence, exposure, and biological effects

B Scholz, S Guth, KH Engel… - Molecular nutrition & …, 2015 - Wiley Online Library
Hypercholesterolemia is an important risk factor for the development of cardiovascular
diseases. Dietary intake of phytosterols/phytostanols and their fatty acid esters results in a …