High expression of EpCAM and the tetraspanin CO-029 has been associated with colorectal
cancer progression. However, opposing results have been reported on CD44 variant …

Background The molecular mechanisms underlying innate tumor drug resistance, a major
obstacle to successful cancer therapy, remain poorly understood. In colorectal cancer …

Tumor metastasis remains the principal cause of treatment failure and poor prognosis in
patients with colorectal cancer. It is a multistage process which includes proteolysis, motility …

CD44 standard isoform (CD44s) is a cancer stem cell marker in many tumors, and is one of
the CD44 isoforms. CD44v6 has been reported to correlate with tumor progression and poor …

Ezrin is a membrane-cytoskeleton anchor, which, in experimental models, regulates tumor
cell invasion and metastatic ability. We carried out immunohistochemical analysis of ezrin in …

Simple Summary In our study, we analyzed the role of CD44 expression as a prognostic
marker in patients with metastatic colorectal cancer. CD44 is a multi-structural and …

Simple Summary CD44 is a crucial factor in colorectal cancer, with specific isoforms
demonstrating their significance in the development, progression, metastasis, and …

BACKGROUND Chloride channel accessory 1 (CLCA1) is a CLCA protein that plays a
functional role in regulating the differentiation and proliferation of colorectal cancer (CRC) …

AIM: To investigate the changes that occur in E-cadherin expression during the process of
metastasis in colorectal cancer. METHODS: E-cadherin expression was detected by …

AIM: To investigate the changing pattern of β-catenin expression and its prognostic value in
advanced colorectal cancer (CRC). METHODS: Archival tumor samples were analyzed for β …