Plant-based natural products for the discovery and development of novel anthelmintics against nematodes
Intestinal parasitic nematodes infect approximately two billion people worldwide. In the
absence of vaccines for human intestinal nematodes, control of infections currently relies …
absence of vaccines for human intestinal nematodes, control of infections currently relies …
An appraisal of natural products active against parasitic nematodes of animals
Here, the scientific and patent literature on the activities of purified natural compounds has
been reviewed, with the aim of assessing their suitability as anthelmintic drug discovery …
been reviewed, with the aim of assessing their suitability as anthelmintic drug discovery …
Therapeutic applications of natural products in herbal medicines, biodiscovery programs, and biomedicine
P Wangchuk - Journal of Biologically Active Products from Nature, 2018 - Taylor & Francis
Natural products had been one of the important sources of remedial agents for thousands of
years. From the data presented in this review, the utilization of biologically active natural …
years. From the data presented in this review, the utilization of biologically active natural …
Natural-product-based solutions for tropical infectious diseases
About half of the world's population and 80% of the world's biodiversity can be found in the
tropics. Many diseases are specific to the tropics, with at least 41 diseases caused by …
tropics. Many diseases are specific to the tropics, with at least 41 diseases caused by …
[HTML][HTML] An automated high-throughput system for phenotypic screening of chemical libraries on C. elegans and parasitic nematodes
FA Partridge, AE Brown, SD Buckingham… - International Journal for …, 2018 - Elsevier
Parasitic nematodes infect hundreds of millions of people and farmed livestock. Further,
plant parasitic nematodes result in major crop damage. The pipeline of therapeutic …
plant parasitic nematodes result in major crop damage. The pipeline of therapeutic …
Natural products for infectious microbes and diseases: an overview of sources, compounds, and chemical diversities
L Luo, J Yang, C Wang, J Wu, Y Li, X Zhang… - Science China Life …, 2022 - Springer
Abstract As coronavirus disease 2019 (COVID-19) threatens human health globally,
infectious disorders have become one of the most challenging problem for the medical …
infectious disorders have become one of the most challenging problem for the medical …
Natural products as anthelmintics: safeguarding animal health
Covering literature to December 2022 This review provides a comprehensive account of all
natural products (500 compounds, including 17 semi-synthetic derivatives) described in the …
natural products (500 compounds, including 17 semi-synthetic derivatives) described in the …
Therapeutic administration of Luteolin protects against Escherichia coli-derived Lipopolysaccharide-triggered inflammatory response and oxidative injury
Endometritis reduces reproductive effectiveness and leads to significant financial losses in
the dairy sector. Luteolin is a natural phyto-flavonoid compound with many biological …
the dairy sector. Luteolin is a natural phyto-flavonoid compound with many biological …
Drug discovery technologies: Caenorhabditis elegans as a model for anthelmintic therapeutics
D Sepúlveda‐Crespo, RM Reguera… - Medicinal research …, 2020 - Wiley Online Library
Helminthiasis is one of the gravest problems worldwide. There is a growing concern on less
available anthelmintics and the emergence of resistance creating a major threat to human …
available anthelmintics and the emergence of resistance creating a major threat to human …
Metabolomic profiling of the excretory–secretory products of hookworm and whipworm
P Wangchuk, K Kouremenos, RM Eichenberger… - Metabolomics, 2019 - Springer
Introduction Soil-transmitted helminths infect billions of people, livestock and companion
animals worldwide, and chronic infections with these nematodes represent a major health …
animals worldwide, and chronic infections with these nematodes represent a major health …