Bacteriophage and bacterial susceptibility, resistance, and tolerance to antibiotics

Q Chen, T Dharmaraj, PC Cai, EB Burgener… - Pharmaceutics, 2022 - mdpi.com
Bacteriophages, viruses that infect and replicate within bacteria, impact bacterial responses
to antibiotics in complex ways. Recent studies using lytic bacteriophages to treat bacterial …

A filamentous bacteriophage protein inhibits type IV pili to prevent superinfection of Pseudomonas aeruginosa

AK Schmidt, AD Fitzpatrick, CM Schwartzkopf, DR Faith… - MBio, 2022 - Am Soc Microbiol
Pseudomonas aeruginosa is an opportunistic pathogen that causes infections in a variety of
settings. Many P. aeruginosa isolates are infected by filamentous Pf bacteriophage …

Bacterial outer membrane vesicles bound to bacteriophages modulate neutrophil responses to bacterial infection

N Pennetzdorfer, MC Popescu, NL Haddock… - Frontiers in Cellular …, 2023 - frontiersin.org
Pseudomonas aeruginosa is a major human pathogen, particularly effective at colonizing
the airways of patients with cystic fibrosis. Bacteriophages are highly abundant at infection …

Homogenization modelling of antibiotic diffusion and adsorption in viral liquid crystals

MT van Rossem, S Wilks, PR Secor… - Royal Society …, 2023 - royalsocietypublishing.org
Systems of rod-shaped viruses have long been important to the science of living liquid
crystals, as their monodispersity and uniform charge make them convenient model systems …

Phage–Antibiotic Synergy Inhibited by Temperate and Chronic Virus Competition

KJ Landa, LM Mossman, RJ Whitaker, Z Rapti… - Bulletin of Mathematical …, 2022 - Springer
As antibiotic resistance grows more frequent for common bacterial infections, alternative
treatment strategies such as phage therapy have become more widely studied in the …

Modelling the effects of charge on antibiotic diffusion and adsorption in liquid crystalline virus suspensions

MT van Rossem, S Wilks, M Kaczmarek… - Soft Matter, 2024 - pubs.rsc.org
We develop a microscopic model of antibiotic diffusion in virus suspensions in a liquid
crystalline state. We then approximate this with an effective homogenised model that is more …

Pf bacteriophage inhibits neutrophil migration in the lung

MC Popescu, N Pennetzdorfer, A Hargil, G Kaber… - bioRxiv, 2022 - biorxiv.org
Bacteriophages are abundant in the human body, including at sites of infection. We report
that Pf4 phage, a filamentous bacteriophage produced by Pseudomonas aeruginosa …