Physics and biology of ultrahigh dose-rate (FLASH) radiotherapy: a topical review

N Esplen, MS Mendonca… - Physics in Medicine & …, 2020 - iopscience.iop.org
Ultrahigh dose-rate radiotherapy (RT), or'FLASH'therapy, has gained significant momentum
following various in vivo studies published since 2014 which have demonstrated a reduction …

Dosimetry of small static fields used in external photon beam radiotherapy: summary of TRS‐483, the IAEA–AAPM international Code of Practice for reference and …

H Palmans, P Andreo, MS Huq, J Seuntjens… - Medical …, 2018 - Wiley Online Library
Purpose A joint IAEA/AAPM international working group has developed a Code of Practice
(CoP) for the dosimetry of small static fields used in external megavoltage photon beam …

Report of AAPM task group 235 radiochromic film dosimetry: an update to TG‐55

A Niroomand‐Rad, ST Chiu‐Tsao, MP Grams… - Medical …, 2020 - Wiley Online Library
The use of radiochromic film (RCF) dosimetry in radiation therapy is extensive due to its high
level of achievable accuracy for a wide range of dose values and its suitability under a …

AAPM Task Group 198 Report: An implementation guide for TG 142 quality assurance of medical accelerators

J Hanley, S Dresser, W Simon, R Flynn… - Medical …, 2021 - Wiley Online Library
The charges on this task group (TG) were as follows:(a) provide specific procedural
guidelines for performing the tests recommended in TG 142;(b) provide estimate of the …

Reference dosimetry in magnetic fields: formalism and ionization chamber correction factors

DJ O'Brien, DA Roberts, GS Ibbott… - Medical …, 2016 - Wiley Online Library
Purpose: Magnetic resonance imaging–guided radiotherapy (MRIgRT) provides superior
soft‐tissue contrast and real‐time imaging compared with standard image‐guided RT, which …

Review on the characteristics of radiation detectors for dosimetry and imaging

J Seco, B Clasie, M Partridge - Physics in Medicine & Biology, 2014 - iopscience.iop.org
The enormous advances in the understanding of human anatomy, physiology and pathology
in recent decades have led to ever-improving methods of disease prevention, diagnosis and …

Flattening filter‐free accelerators: a report from the AAPM Therapy Emerging Technology Assessment Work Group

Y Xiao, SF Kry, R Popple, E Yorke… - Journal of applied …, 2015 - Wiley Online Library
This report describes the current state of flattening filter‐free (FFF) radiotherapy beams
implemented on conventional linear accelerators, and is aimed primarily at practicing …

Commissioning of a 1.5 T Elekta Unity MR‐linac: a single institution experience

JE Snyder, J St‐Aubin, S Yaddanapudi… - Journal of applied …, 2020 - Wiley Online Library
MR image‐guided radiotherapy has the potential to improve patient care, but integration of
an MRI scanner with a linear accelerator adds complexity to the commissioning process …

A roadmap to clinical trials for FLASH

PA Taylor, JM Moran, DA Jaffray… - Medical …, 2022 - Wiley Online Library
While FLASH radiation therapy is inspiring enthusiasm to transform the field, it is neither new
nor well understood with respect to the radiobiological mechanisms. As FLASH clinical trials …

[HTML][HTML] Framework for quality assurance of ultrahigh dose rate clinical trials investigating FLASH effects and current technology gaps

W Zou, R Zhang, E Schüler, PA Taylor… - International Journal of …, 2023 - Elsevier
Abstract FLASH radiation therapy (FLASH-RT), delivered with ultrahigh dose rate (UHDR),
may allow patients to be treated with less normal tissue toxicity for a given tumor dose …