Biofilms are surface‐adhered bacterial communities encased in an extracellular matrix
composed of polysaccharides, proteins, and extracellular (e) DNA, with eDNA required for …

Summary Plakoglobin (γ-catenin), a constituent of the adherens junction and desmosomes,
has signaling capabilities typically associated with tumor/metastasis suppression through …

Mutant (Mt) p53 abrogates tumor suppression functions of wild-type (WT) p53 through
mutant-specific, gain-of-function effects, and patients bearing Mt p53 are chemoresistant …

Stress treatment generally causes the post-translational modification and accumulation of
the p53 protein, although the role of these aspects has not been always understood in …

The chemotherapeutic agents doxorubicin (dox) or 5-fluorouracil (5FU) are used to treat
cancer cells as they cause irreparable DNA damage, inducing these aberrant cells to …

The scattering of light redirects and resonances when an electromagnetic wave interacts
with electrons orbits in the hot spot core protein and oscillated electron of the gold …

Measurement of the level of a specific protein can be an important parameter to discern as
that can change and reflect disease status. A number of methods have been developed to …

Abnormalities in several important cellular pathways and processes are often a major
contributing factor to the progression of cancer. The cell cycle is regulated by checkpoint …

Detecting or intervening in biomolecular processes for medical diagnostics, drug delivery,
and bacterial inactivation requires a functional probe which interfaces not only the targeted …

Nádorové supresory hrají důležitou úlohu v ochraně buňky před rakovinným bujením. U
mnoha těchto proteinů je jejich funkce zprostředkována na základě protein-protein a protein …