Decreased antimicrobial efficiency has become a global public health issue. The paucity of
new antibacterial drugs is evident, and the arsenal against infectious diseases needs to be …

The bacterial flagellum is an amazingly complex molecular machine with a diversity of roles
in pathogenesis including reaching the optimal host site, colonization or invasion …

Commensal and pathogenic microorganisms must resist the deleterious actions of bile in
order to survive in the human gastrointestinal tract. Herein we review the current knowledge …

As locomotive organelles, flagella allow bacteria to move toward favorable environments. A
flagellum consists of three parts: the basal structure (rotary motor), the hook (universal joint) …

Vibrio cholerae is the causative agent of the diarrheal disease cholera. By an incompletely
understood developmental process, V. cholerae forms complex surface-associated …

Flagella contribute to the virulence of pathogenic bacteria through chemotaxis, adhesion to
and invasion of host surfaces. Flagellin is the structural protein that forms the major portion …

Cholera is a frightening disease. Victims are wracked by stomach cramps and suffer intense
diarrhoea. Death can come within hours. Though now seeming a distant memory in Europe …

It is now apparent that the signaling molecule 3′, 5′-cyclic diguanylic acid (c-di-GMP) is a
central regulator of the prokaryote biofilm lifestyle and recent evidence also links this …

Pathogens adapt to the host environment by altering their patterns of gene expression.
Microarray-based and genetic techniques used to characterize bacterial gene expression …

N-acylhomoserine lactone-dependent quorum sensing was first discovered in two
luminescent marine bacteria, Vibrio fischeri and Vibrio harveyi. The LuxI/R system of V …