The oral administration of therapeutic peptides and proteins is favoured from a patient and
commercial point of view. In order to reach the systemic circulation after oral administration …

Antibody therapeutics are a large and rapidly expanding drug class providing major health
benefits. We provide a snapshot of current antibody therapeutics including their formats …

Oral drug administration has been a popular choice due to patient compliance and limited
clinical resources. Orally delivered drugs must circumvent the harsh gastrointestinal (GI) …

Among other health related issues, the rising concerns on drug resistance led to look for
alternative pharmaceutical drugs that are effective both against infectious and noninfectious …

In recent years, the occurrence of a wide variety of drug-resistant diseases has led to an
increase in interest in alternate therapies. Peptide-based drugs as an alternate therapy hold …

Hydrogels have a tridimensional structure. They have the ability to absorb a significant
amount of water or other natural or simulated fluids that cause their swelling albeit without …

As a group of chronic and idiopathic gastrointestinal (GI) disorders, inflammatory bowel
disease (IBD) is characterized by recurrent intestinal mucosal inflammation. Oral …

Therapeutic proteins are playing increasingly important roles in treating numerous types of
diseases. However, oral administration of proteins, especially large ones (eg, antibodies) …

Protein and peptide drugs are predominantly administered by injection to achieve high
bioavailability, but this greatly compromises patient compliance. Oral and transdermal drug …

In the last two decades, protein–protein interactions (PPIs) have been used as the main
target for drug development. However, with larger or superficial binding sites, it has been …