Half a century of amyloids: past, present and future
Amyloid diseases are global epidemics with profound health, social and economic
implications and yet remain without a cure. This dire situation calls for research into the …
implications and yet remain without a cure. This dire situation calls for research into the …
Metallo-β-lactamases in the age of multidrug resistance: from structure and mechanism to evolution, dissemination, and inhibitor design
G Bahr, LJ Gonzalez, AJ Vila - Chemical reviews, 2021 - ACS Publications
Antimicrobial resistance is one of the major problems in current practical medicine. The
spread of genes coding for resistance determinants among bacteria challenges the use of …
spread of genes coding for resistance determinants among bacteria challenges the use of …
From squiggle to basepair: computational approaches for improving nanopore sequencing read accuracy
FJ Rang, WP Kloosterman, J de Ridder - Genome biology, 2018 - Springer
Nanopore sequencing is a rapidly maturing technology delivering long reads in real time on
a portable instrument at low cost. Not surprisingly, the community has rapidly taken up this …
a portable instrument at low cost. Not surprisingly, the community has rapidly taken up this …
Multi-pass, single-molecule nanopore reading of long protein strands
The ability to sequence single protein molecules in their native, full-length form would
enable a more comprehensive understanding of proteomic diversity. Current technologies …
enable a more comprehensive understanding of proteomic diversity. Current technologies …
UroPathogenic Escherichia coli (UPEC) Infections: Virulence Factors, Bladder Responses, Antibiotic, and Non-antibiotic Antimicrobial Strategies
ME Terlizzi, G Gribaudo, ME Maffei - Frontiers in microbiology, 2017 - frontiersin.org
Urinary tract infections (UTIs) are one of the most common pathological conditions in both
community and hospital settings. It has been estimated that about 150 million people …
community and hospital settings. It has been estimated that about 150 million people …
Recent innovations in bacterial infection detection and treatment
C Deusenbery, Y Wang, A Shukla - ACS Infectious Diseases, 2021 - ACS Publications
Bacterial infections are a major threat to human health, exacerbated by increasing antibiotic
resistance. These infections can result in tremendous morbidity and mortality, emphasizing …
resistance. These infections can result in tremendous morbidity and mortality, emphasizing …
Nanopore sequencing: Review of potential applications in functional genomics
Molecular biology has been led by various measurement technologies, and increased
throughput has developed omics analysis. The development of massively parallel …
throughput has developed omics analysis. The development of massively parallel …
Three decades of nanopore sequencing
A long-held goal in sequencing has been to use a voltage-biased nanoscale pore in a
membrane to measure the passage of a linear, single-stranded (ss) DNA or RNA molecule …
membrane to measure the passage of a linear, single-stranded (ss) DNA or RNA molecule …
DNA methylation-calling tools for Oxford Nanopore sequencing: a survey and human epigenome-wide evaluation
Background Nanopore long-read sequencing technology greatly expands the capacity of
long-range, single-molecule DNA-modification detection. A growing number of analytical …
long-range, single-molecule DNA-modification detection. A growing number of analytical …
Secretion systems in Gram-negative bacteria: structural and mechanistic insights
Bacteria have evolved a remarkable array of sophisticated nanomachines to export various
virulence factors across the bacterial cell envelope. In recent years, considerable progress …
virulence factors across the bacterial cell envelope. In recent years, considerable progress …