Macrophages are involved in almost every aspect of biological systems and include
development, homeostasis and repair. Mesenchymal stem cells (MSCs) have good clinical …

Simple Summary Transforming growth factor beta (TGF-β) is a multifunctional cytokine that
can restrict cancer onset but also promote cancer progression at late stages of cancer. The …

Immunosuppressive tumor microenvironments (TMEs) reduce the effectiveness of immune
responses in cancer. Mesenchymal stromal cells (MSCs), precursors to cancer-associated …

Mesenchymal stem/stromal cells (MSCs) have been evaluated in> 1500 clinical trials, but
outcomes remain suboptimal because of knowledge gaps in quality attributes that confer …

Mesenchymal stromal cells (MSCs) and MSC-derived extracellular vesicles (EVs) have
emerged as innovative therapeutic agents for the treatment of sepsis and acute respiratory …

Background Adipose tissue-derived stem cell (ADSC) transplantation has been shown to be
effective for the management of severe liver disorders. Preactivation of ADSCs enhanced …

Abstract Background Mesenchymal stromal cells (MSCs) show great potential for
immunomodulatory and anti-inflammatory treatments. Clinical trials have been performed for …

Adult tissue-specific stem cells play a dominant role in tissue homeostasis and regeneration.
Various in vivo markers of adult tissue-specific stem cells have been increasingly reported …

More than 10% of the world's population suffers from osteoarthritis (OA) of the knee, with a
lifetime risk of 45%. Current treatments for knee OA pain are as follows: weight control; oral …

Recent clinical trials of mesenchymal stromal cell (MSC) therapy for various inflammatory
conditions have highlighted the significant benefit to patients who respond to MSC …