During oncogenesis, cancer not only escapes the body's regulatory mechanisms, but also
gains the ability to affect local and systemic homeostasis. Specifically, tumors produce …

The skin is the largest organ and has a key protective role. Similar to any other tissue, the
skin is influenced not only by intrinsic/chronological aging, but also by extrinsic aging …

The skin, which is comprised of the epidermis, dermis, and subcutaneous tissue, is the
largest organ in the human body and it plays a crucial role in the regulation of the body's …

The skin, being the largest organ in the human body, is exposed to the environment and
suffers from both intrinsic and extrinsic aging factors. The skin aging process is …

UV radiation (UV) is classified as a “complete carcinogen” because it is both a mutagen and
a non-specific damaging agent and has properties of both a tumor initiator and a tumor …

The active metabolites of vitamin D3 (D3) and lumisterol (L3) exert a variety of antiaging and
photoprotective effects on the skin. These are achieved through immunomodulation and …

Purpose Although scientific articles mention the impact of psychological stress on skin
diseases, few review the latest research on factors involved in this correlation. The skin …

Melatonin production is highly conserved in nature through different species including
bacteria, unicellular eukaryotes, algae, plants invertebrates, and vertebrates (Hardeland et …

Mast cells are well known for their role in allergic and anaphylactic reactions, as well as their
involvement in acquired and innate immunity. Increasing evidence now implicates mast cells …

The discovery of corticotropin-releasing factor (CRF) or CRH defining the upper regulatory
arm of the hypothalamic-pituitary-adrenal (HPA) axis, along with the identification of the …