Engineering drought tolerance in plants: discovering and tailoring genes to unlock the future

T Umezawa, M Fujita, Y Fujita… - Current opinion in …, 2006 - Elsevier
The ability of plants to tolerate drought conditions is crucial for agricultural production
worldwide. Recent progress has been made in our understanding of gene expression …

[HTML][HTML] Multidrug resistance in fungi: regulation of transporter-encoding gene expression

S Paul, WS Moye-Rowley - Frontiers in physiology, 2014 - frontiersin.org
A critical risk to the continued success of antifungal chemotherapy is the acquisition of
resistance; a risk exacerbated by the few classes of effective antifungal drugs. Predictably …

AREB1 Is a Transcription Activator of Novel ABRE-Dependent ABA Signaling That Enhances Drought Stress Tolerance in Arabidopsis

Y Fujita, M Fujita, R Satoh, K Maruyama… - The Plant …, 2005 - academic.oup.com
Abstract ABSCISIC ACID–RESPONSIVE ELEMENT BINDING PROTEIN1 (AREB1)(ie,
ABF2) is a basic domain/leucine zipper transcription factor that binds to the abscisic acid …

[HTML][HTML] Genome‐wide analysis of mRNAs targeted to yeast mitochondria

P Marc, A Margeot, F Devaux, C Blugeon… - EMBO …, 2002 - embopress.org
It is agreed that nuclear‐encoded mitochondrial proteins are post‐translationally targeted to
mitochondria, even if, in some cases, a co‐translational phase can assist the import of …

Pdr1 regulates multidrug resistance in Candida glabrata: gene disruption and genome‐wide expression studies

JP Vermitsky, KD Earhart, WL Smith… - Molecular …, 2006 - Wiley Online Library
Candida glabrata emerged in the last decade as a common cause of mucosal and invasive
fungal infection, in large part due to its intrinsic or acquired resistance to azole antifungals …

Identifying transcription factor functions and targets by phenotypic activation

G Chua, QD Morris, R Sopko… - Proceedings of the …, 2006 - National Acad Sciences
Mapping transcriptional regulatory networks is difficult because many transcription factors
(TFs) are activated only under specific conditions. We describe a generic strategy for …

Loss of mitochondrial functions associated with azole resistance in Candida glabrata results in enhanced virulence in mice

S Ferrari, M Sanguinetti, F De Bernardis… - Antimicrobial agents …, 2011 - Am Soc Microbiol
Mitochondrial dysfunction is one of the possible mechanisms by which azole resistance can
occur in Candida glabrata. Cells with mitochondrial DNA deficiency (so-called “petite …

The ATP‐binding cassette transporter–encoding gene CgSNQ2 is contributing to the CgPDR1‐dependent azole resistance of Candida glabrata

R Torelli, B Posteraro, S Ferrari… - Molecular …, 2008 - Wiley Online Library
Our previous investigation on Candida glabrata azole‐resistant isolates identified two
isolates with unaltered expression of CgCDR1/CgCDR2, but with upregulation of another …

[HTML][HTML] Contribution of CgPDR1-Regulated Genes in Enhanced Virulence of Azole-Resistant Candida glabrata

S Ferrari, M Sanguinetti, R Torelli, B Posteraro… - PloS one, 2011 - journals.plos.org
In Candida glabrata, the transcription factor CgPdr1 is involved in resistance to azole
antifungals via upregulation of ATP binding cassette (ABC)-transporter genes including at …

The yeast zinc finger regulators Pdr1p and Pdr3p control pleiotropic drug resistance (PDR) as homo‐ and heterodimers in vivo

YM Mamnun, R Pandjaitan, Y Mahé… - Molecular …, 2002 - Wiley Online Library
The transcription factors Pdr1p and Pdr3p from Saccharomyces cerevisiae mediate
pleiotropic drug resistance (PDR) by controlling expression of ATP‐binding cassette (ABC) …