The BCl-2 family has long been identified for its role in apoptosis. Following the initial
discovery of BCL-2 in the context of B-cell lymphoma in the 1980s, a number of homologous …

The previous decade has seen long non-coding RNAs (lncRNAs) rise from obscurity to
being defined as a category of genetic elements, leaving its mark on the field of cancer …

Examples of associations between human disease and defects in pre–messenger RNA
splicing/alternative splicing are accumulating. Although many alterations are caused by …

Most human genes encode multiple mRNA variants and protein products through alternative
splicing of exons and introns during pre-mRNA processing. In this way, alternative splicing …

Prostate cancer (PCa) is one of the major men malignancies worldwide. Long noncoding
RNAs (lncRNAs) have been reported as essential regulators in human cancers, including …

Long noncoding RNAs (lncRNAs) play an important role in the development and
progression of cancers. However, the clinical significances of lncRNAs and their functions …

epigallocatechin-3-gallate (EGCG), the major bioactive catechin in green tea (GT) has been
studied for almost past thirty years as an agent initially for its cancer chemoprevention effects …

LincRNA-p21 is a long noncoding RNA and a transcriptional target of p53 and HIF-1α.
LincRNA-p21 regulates gene expression in cis and trans, mRNA translation, protein stability …

Increasing evidence shows that long noncoding RNAs (lncRNAs) have important roles in the
regulation of multiple cellular processes, including cell division, cell growth, and apoptosis …

Non-coding RNA (ncRNA) comprises a substantial portion of primary transcripts that are
generated by genomic transcription, but are not translated into protein. The possible …