Type 2 Diabetes Mellitus (T2DM), one of the most common metabolic disorders, is caused
by a combination of two primary factors: defective insulin secretion by pancreatic β-cells and …

With cardiovascular disease being the leading cause of morbidity and mortality worldwide,
effective and cost-efficient therapies to reduce cardiovascular risk are highly needed. Lipids …

Excess intra-abdominal adipose tissue accumulation, often termed visceral obesity, is part of
a phenotype including dysfunctional subcutaneous adipose tissue expansion and ectopic …

Infection and inflammation induce the acutephase response (APR), leading to multiple
alterations in lipid and lipoprotein metabolism. Plasma triglyceride levels increase from …

The metabolic syndrome (MetS) is comprised of a cluster of closely related risk factors,
including visceral adiposity, insulin resistance, hypertension, high triglyceride, and low high …

The metabolism of high-density lipoproteins (HDL), which are inversely related to risk of
atherosclerotic cardiovascular disease, involves a complex interplay of factors regulating …

The recognition that the increase of plasma triglyceride rich lipoproteins (TRLs) is
associated with multiple alterations of other lipoproteins species that are potentially …

Since the first discovery of an inverse correlation between high‐density lipoprotein‐
cholesterol (HDL‐C) levels and coronary heart disease in the 1950s the life cycle of HDL, its …

Research into lipoprotein metabolism has developed because understanding lipoprotein
metabolism has important clinical indications. Lipoproteins are risk factors for cardiovascular …

Subnormal plasma levels of high-density lipoprotein cholesterol (HDL-C) constitute a major
cardiovascular risk factor; raising low HDL-C levels may therefore reduce the residual …