Currently, enhancement of cholinergic neurotransmission via cholinesterase inhibitors
represents the main available approach to treat cognitive and behavioural symptoms of the …

Alzheimer disease (AD) represents an oncoming epidemic that without an effective
treatment promises to exact extraordinary financial and emotional burdens. Studies of …

Brain-derived neurotrophic factor (BDNF) is a small dimeric protein, structurally related to
nerve growth factor, which is abundantly and widely expressed in the adult mammalian …

Alzheimer's disease (AD) is the most common form of degenerative dementia and is
characterized by progressive impairment in cognitive function during mid-to late-adult life …

The decline observed during aging involves multiple factors that influence several systems.
It is the case for learning and memory processes which are severely reduced with aging. It is …

Background Nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF),
neurotrophin 3 (NT-3), and neurotrophin 4/5 (NT-4/5) are members of the neurotrophin gene …

Nerve growth factor (NGF) is important for regulation, differentiation, and survival of
peripheral and central nervous system neurons, including basal forebrain cholinergic …

The biomedical literature on the subject of neurotrophic growth factors has expanded
prodigiously. This essay reviews neurotrophic factors (NTF) and their receptors in …

Neurotrophic factors (NTF) are small, versatile proteins that maintain survival and function to
specific neuronal populations. In general, the axonal transport of NTF is important as not all …

Brain-derived neurotrophic factor (BDNF) attracts increasing attention from both research
and clinical fields because of its important functions in the central nervous system. An …