Fibrillar collagen: a review of the mechanical modeling of strain-mediated enzymatic turnover

H Topol, H Demirkoparan… - Applied …, 2021 - asmedigitalcollection.asme.org
Collagen is the most abundant protein in mammals, often serving as the main load bearing
constituent in soft tissues. Collagen undergoes continuous remodeling processes in which …

[HTML][HTML] Current state-of-the-art and utilities of machine learning for detection, monitoring, growth prediction, rupture risk assessment, and post-surgical management …

S Baek, A Arzani - Applications in Engineering Science, 2022 - Elsevier
Ultrasound imaging has long been playing a central role in detecting abdominal aortic
aneurysms (AAAs). With a recent trend of reducing prevalence of AAAs, ultrasound …

Mechanical and structural changes in human thoracic aortas with age

M Jadidi, M Habibnezhad, E Anttila, K Maleckis… - Acta biomaterialia, 2020 - Elsevier
Aortic mechanical and structural characteristics have profound effects on pathophysiology,
but many aspects of physiologic stress-stretch state and intramural changes due to aging …

Material properties of the posterior human sclera

R Grytz, MA Fazio, MJA Girard, V Libertiaux… - Journal of the …, 2014 - Elsevier
To characterize the material properties of posterior and peripapillary sclera from human
donors, and to investigate the macro-and micro-scale strains as potential control …

Biomechanical rupture risk assessment of abdominal aortic aneurysms based on a novel probabilistic rupture risk index

S Polzer, TC Gasser - Journal of The Royal Society …, 2015 - royalsocietypublishing.org
A rupture risk assessment is critical to the clinical treatment of abdominal aortic aneurysm
(AAA) patients. The biomechanical AAA rupture risk assessment quantitatively integrates …

Biomechanical properties of the thoracic aneurysmal wall: differences between bicuspid aortic valve and tricuspid aortic valve patients

C Forsell, HM Björck, P Eriksson… - The Annals of thoracic …, 2014 - Elsevier
Background The prevalence for thoracic aortic aneurysms (TAAs) is significantly increased
in patients with a bicuspid aortic valve (BAV) compared with patients who have a normal …

A quarter of a century biomechanical rupture risk assessment of abdominal aortic aneurysms. Achievements, clinical relevance, and ongoing developments

TC Gasser, C Miller, S Polzer… - International journal for …, 2023 - Wiley Online Library
Abdominal aortic aneurysm (AAA) disease, the local enlargement of the infrarenal aorta, is a
serious condition that causes many deaths, especially in men exceeding 65 years of age …

Age-dependent changes of stress and strain in the human heart valve and their relation with collagen remodeling

PJA Oomen, S Loerakker, D van Geemen, J Neggers… - Acta biomaterialia, 2016 - Elsevier
In order to create tissue-engineered heart valves with long-term functionality, it is essential to
fully understand collagen remodeling during neo-tissue formation. Collagen remodeling is …

Parametric study of effects of collagen turnover on the natural history of abdominal aortic aneurysms

JS Wilson, S Baek… - Proceedings of the …, 2013 - royalsocietypublishing.org
Abdominal aortic aneurysms (AAAs) are characterized by significant changes in the
architecture of the aortic wall, notably, loss of functional elastin and smooth muscle. Because …

Predicting and understanding arterial elasticity from key microstructural features by bidirectional deep learning

K Linka, C Cavinato, JD Humphrey, CJ Cyron - Acta biomaterialia, 2022 - Elsevier
Microstructural features and mechanical properties are closely related in all soft biological
tissues. Both yet exhibit considerable inter-individual differences and are affected by factors …