Axonal regeneration and formation of tripartite (axo-glial) junctions at damaged sites is a
prerequisite for early repair of injured spinal cord. Transplantation of stem cells at such sites …

Cell transplantation therapies have become a major focus in pre-clinical research as a
promising strategy for the treatment of spinal cord injury (SCI). In this article, we …

The rationale for implantation of autologous human Schwann cells (SCs) in persons with
subacute spinal cord injury (SCI) is based on evidence that transplanted SCs are …

Evidence that cell transplants can improve recovery outcomes in spinal cord injury (SCI)
models substantiates treatment strategies involving cell replacement for humans with SCI …

A phase 1 open-label, non-randomized clinical trial was conducted to determine feasibility
and safety of autologous human Schwann cell (ahSC) transplantation accompanied by …

Spinal cord injury (SCI) is a devastating and complicated condition with no cure available.
The initial mechanical trauma is followed by a secondary injury characterized by …

Abstract Transplantation of Schwann cells (SCs) is a promising therapeutic strategy for
spinal cord repair. The introduction of SCs into the injured spinal cord has been shown to …

Object Many experimental studies on spinal cord injuries (SCIs) support behavioral
improvement after Schwann cell treatment. This study was conducted to evaluate safety …

Chronic spinal cord injury (SCI) is characterized by tissue loss and a stable functional deficit.
While several experimental therapies have proven to be partly successful for the treatment of …

Myelin sheaths, by supporting axonal integrity and allowing rapid saltatory impulse
conduction, are of fundamental importance for neuronal function. In response to …