Recent studies in PKU patients identified alternative biomarkers in blood using untargeted
metabolomics. To test the added clinical value of these novel biomarkers, targeted …

Phenylketonuria (PKU) is a rare metabolic disorder caused by mutations in the
phenylalanine hydroxylase gene. Depending on the severity of the genetic mutation …

The question of an increased cardiovascular risk has been recently raised in adults with
phenylketonuria (PKU). As low‐grade systemic inflammation increases cardiovascular risk …

Background: Cardiac magnetic resonance (CMR) imaging with gadolinium-based contrast
agents offers unique non-invasive insights into cardiac tissue composition. Myocardial …

Objectives To compare the glycemic index (GI), obesity, echocardiographic, and arterial
stiffness measurements with the healthy control group to evaluate the cardiovascular risk of …