Polycyclic aromatic hydrocarbons (PAHs): Updated aspects of their determination, kinetics in the human body, and toxicity
Polycyclic aromatic hydrocarbons (PAHs) are legacy pollutants of considerable public health
concern. Polycyclic aromatic hydrocarbons arise from natural and anthropogenic sources …
concern. Polycyclic aromatic hydrocarbons arise from natural and anthropogenic sources …
Applicability of in vitro methods in evaluating the biotransformation of polycyclic aromatic hydrocarbons (PAHs) in fish: Advances and challenges
The biotransformation of polycyclic aromatic hydrocarbons (PAHs) and the biochemical
mechanisms involved in such process continue to be intensively studied in the fields of …
mechanisms involved in such process continue to be intensively studied in the fields of …
Newly identified AhR-active compounds in the sediments of an industrial area using effect-directed analysis
Effect-directed analysis was used to identify previously unidentified aryl hydrocarbon
receptor (AhR) agonists in sediments collected from a highly industrialized area of Ulsan …
receptor (AhR) agonists in sediments collected from a highly industrialized area of Ulsan …
Endocrine disrupting potential of PAHs and their alkylated analogues associated with oil spills
Polycyclic aromatic hydrocarbons (PAHs) and alkylated PAHs are known to be major toxic
contaminants in spills of petroleum hydrocarbons (oil). Spilled oil undergoes weathering and …
contaminants in spills of petroleum hydrocarbons (oil). Spilled oil undergoes weathering and …
Assessment of the aryl hydrocarbon receptor-mediated activities of polycyclic aromatic hydrocarbons in a human cell-based reporter gene assay
J Vondráček, K Pěnčíková, J Neča, M Ciganek… - Environmental …, 2017 - Elsevier
Activation of the aryl hydrocarbon receptor (AhR)-mediated activity is one of key events in
toxicity of polycyclic aromatic hydrocarbons (PAHs). Although various classes of AhR …
toxicity of polycyclic aromatic hydrocarbons (PAHs). Although various classes of AhR …
A polycyclic aromatic hydrocarbon-enriched environmental chemical mixture enhances AhR, antiapoptotic signaling and a proliferative phenotype in breast cancer …
LM Gearhart-Serna, JB Davis, MK Jolly… - …, 2020 - academic.oup.com
Emerging evidence suggests the role of environmental chemicals, in particular endocrine-
disrupting chemicals (EDCs), in progression of breast cancer and treatment resistance …
disrupting chemicals (EDCs), in progression of breast cancer and treatment resistance …
Methylated PACs are more potent than their parent compounds: A study of aryl hydrocarbon receptor–mediated activity, degradability, and mixture interactions in the …
MM Lam, R Bülow, M Engwall… - Environmental …, 2018 - Wiley Online Library
Twenty‐six polycyclic aromatic compounds (PACs; including native polycyclic aromatic
hydrocarbons [PAHs], hydroxylated PAHs, alkylated and oxygenated PAHs, and [alkylated] …
hydrocarbons [PAHs], hydroxylated PAHs, alkylated and oxygenated PAHs, and [alkylated] …
Aryl hydrocarbon receptor activity of polyhalogenated carbazoles and the molecular mechanism
D Ma, HQ Xie, W Zhang, Q Xue, X Liu, L Xu… - Science of the total …, 2019 - Elsevier
Polyhalogenated carbazoles (PHCZs) are a class of contaminants identified with
persistence and bioaccumulation property from previous studies. However, the toxic effect …
persistence and bioaccumulation property from previous studies. However, the toxic effect …
Contamination characteristics and source apportionment of methylated PAHs in agricultural soils from Yangtze River Delta, China
Abstract Alkylated PAHs (APAHs) have been shown to be more toxic and persistent than
their non-alkylated parent compounds. However, little is known about the extent of soil …
their non-alkylated parent compounds. However, little is known about the extent of soil …
Effect-directed analysis: Current status and future challenges
Abstract Effect-directed analysis (EDA) has become useful for identification of toxicant (s)
that occur in mixtures in the environment, especially those that are causative agents of …
that occur in mixtures in the environment, especially those that are causative agents of …