This review focuses on the multiple and reciprocal relationships that exist between oxidative
stress, hyperglycemia and diabetes and related metabolic disorders. Human metabolism …

Idiopathic pulmonary fibrosis (IPF), the most common form of idiopathic interstitial
pneumonia, is a progressive, irreversible, and typically lethal disease characterized by an …

Oxidative stress plays an important role in the pathogenesis of various chronic liver diseases
(CLD) and increasing evidence have confirmed the contributory role of oxidative stress in …

The novel COVID-19 pandemic is affecting the world's population differently: mostly in the
presence of conditions such as aging, diabetes and hypertension the virus triggers a lethal …

Transforming growth factor beta (TGF-β) is the most potent pro-fibrogenic cytokine and its
expression is increased in almost all of fibrotic diseases. Although signaling through Smad …

Endothelial cells have emerged as key players in SARS-CoV-2 infection and COVID-19
inflammatory pathologies. Dysfunctional endothelial cells can promote chronic inflammation …

Transforming growth factor-β (TGF-β) is a multifunctional cytokine that is involved in
proliferation, metastasis, and many other important processes in malignancy. Inhibitors …

BACKGROUND: Glutathione (GSH) is present in all mammalian tissues as the most
abundant non-protein thiol that defends against oxidative stress. GSH is also a key …

Coronavirus disease (COVID‐19) caused by the novel coronavirus (SARS‐CoV‐2) has
rapidly spread across the globe affecting 213 countries or territories with greater than six …

AGE/RAGE signaling has been a well‐studied cascade in many different disease states,
particularly diabetes. Due to the complex nature of the receptor and multiple intersecting …