The glycosylation in SARS-CoV-2 and its receptor ACE2

Y Gong, S Qin, L Dai, Z Tian - Signal Transduction and Targeted …, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), a highly infectious disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected more than …

Mass spectrometry-based techniques to elucidate the sugar code

M Grabarics, M Lettow, C Kirschbaum, K Greis… - Chemical …, 2021 - ACS Publications
Cells encode information in the sequence of biopolymers, such as nucleic acids, proteins,
and glycans. Although glycans are essential to all living organisms, surprisingly little is …

[PDF][PDF] Wang

Y Wang - Jia Z, Yi Q, Song L. The various components implied …, 2018 - tranassoc.com
Systems and methods are disclosed for communicating data in an integrated sensor network
having one or more nodes coupled to an optical sensor network and a radio frequency …

High-sensitivity analytical approaches for the structural characterization of glycoproteins

WR Alley Jr, BF Mann, MV Novotny - Chemical reviews, 2013 - ACS Publications
1.1. General Considerations Structural intricacies of carbohydrate molecules and their
propensity to form varied linkages, substitutions, and branching patterns have fascinated …

Glycan analysis of therapeutic glycoproteins

L Zhang, S Luo, B Zhang - MAbs, 2016 - Taylor & Francis
Therapeutic monoclonal antibodies (mAbs) are glycoproteins produced by living cell
systems. The glycan moieties attached to the proteins can directly affect protein stability …

Therapeutic monoclonal antibody N-glycosylation–Structure, function and therapeutic potential

F Cymer, H Beck, A Rohde, D Reusch - Biologicals, 2018 - Elsevier
Therapeutic antibodies (IgG-type) contain several post-translational modifications (PTMs)
whereby introducing a large heterogeneity, both structural and functional, into this class of …

Glycan labeling and analysis in cells and in vivo

B Cheng, Q Tang, C Zhang… - Annual Review of …, 2021 - annualreviews.org
As one of the major types of biomacromolecules in the cell, glycans play essential functional
roles in various biological processes. Compared with proteins and nucleic acids, the …

Advances in LC–MS/MS-based glycoproteomics: Getting closer to system-wide site-specific mapping of the N-and O-glycoproteome

M Thaysen-Andersen, NH Packer - … et Biophysica Acta (BBA)-Proteins and …, 2014 - Elsevier
Site-specific structural characterization of glycoproteins is important for understanding the
exact functional relevance of protein glycosylation. Resulting partly from the multiple layers …

Recent advances in hydrophilic interaction liquid chromatography (HILIC) for structural glycomics

G Zauner, AM Deelder, M Wuhrer - Electrophoresis, 2011 - Wiley Online Library
This review presents recent progress in employing hydrophilic interaction liquid
chromatography (HILIC) for glycan and glycopeptides analysis. After an introduction of this …

Reversed-phase separation methods for glycan analysis

GCM Vreeker, M Wuhrer - Analytical and bioanalytical chemistry, 2017 - Springer
Reversed-phase chromatography is a method that is often used for glycan separation. For
this, glycans are often derivatized with a hydrophobic tag to achieve retention on …