The (unusual) heuristic value of Hox gene clusters; a matter of time?

D Duboule - Developmental biology, 2022 - Elsevier
Ever since their first report in 1984, Antennapedia-type homeobox (Hox) genes have been
involved in such a series of interesting observations, in particular due to their conserved …

Temporal regulation of vegetative phase change in plants

RS Poethig, J Fouracre - Developmental Cell, 2024 - cell.com
During their vegetative growth, plants reiteratively produce leaves, buds, and internodes at
the apical end of the shoot. The identity of these organs changes as the shoot develops …

[PDF][PDF] A brief history of the segmentation clock

O Pourquié - Developmental Biology, 2022 - Elsevier
The metameric organization or segmentation of the body is a striking characteristic of many
animal species, including invertebrates such as arthropods or annelids as well as …

How enhancers regulate wavelike gene expression patterns

C Mau, H Rudolf, F Strobl, B Schmid, T Regensburger… - Elife, 2023 - elifesciences.org
A key problem in development is to understand how genes turn on or off at the right place
and right time during embryogenesis. Such decisions are made by non-coding sequences …

Fine-mapping and identification of candidate causal genes for tail length in the Merinolandschaf breed

DK Lagler, E Hannemann, K Eck, J Klawatsch… - Communications …, 2022 - nature.com
Docking the tails of lambs in long-tailed sheep breeds is a common practice worldwide. But
this practice is associated with pain. Breeding for a shorter tail could offer an alternative …

Temporal control of RNAi reveals both robust and labile feedback loops in the segmentation clock of the red flour beetle

F Kaufholz, J Ulrich, MS Hakeemi… - Proceedings of the …, 2024 - National Acad Sciences
Animals from all major clades have evolved a segmented trunk, reflected in the human spine
or the insect segments. These units emerge during embryogenesis from a posterior segment …

SALSA, a genetically encoded biosensor for spatiotemporal quantification of Notch signal transduction in vivo

JM Shaffer, I Greenwald - Developmental cell, 2022 - cell.com
Notch-mediated lateral specification is a fundamental mechanism to resolve stochastic cell
fate choices by amplifying initial differences between equivalent cells. To study how …

[HTML][HTML] Waves, patterns, bifurcations: A tutorial review on the vertebrate segmentation clock

P François, V Mochulska - Physics Reports, 2024 - Elsevier
Proper vertebrae formation relies on a tissue-wide oscillator called the segmentation clock.
Individual cellular oscillators in the presomitic mesoderm are modulated by intercellular …

Evolution of patterning

K Filippopoulou, N Konstantinides - The FEBS journal, 2024 - Wiley Online Library
Developing tissues are patterned in space and time; this enables them to differentiate their
cell types and form complex structures to support different body plans. Although space and …

Patterning, from conifers to consciousness: Turing's theory and order from fluctuations

TC Lacalli - Frontiers in Cell and Developmental Biology, 2022 - frontiersin.org
This is a brief account of Turing's ideas on biological pattern and the events that led to their
wider acceptance by biologists as a valid way to investigate developmental pattern, and of …