DNA origami
Biological materials are self-assembled with near-atomic precision in living cells, whereas
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …
Functionalizing DNA origami to investigate and interact with biological systems
DNA origami has emerged as a powerful method to generate DNA nanostructures with
dynamic properties and nanoscale control. These nanostructures enable complex …
dynamic properties and nanoscale control. These nanostructures enable complex …
Base editing: advances and therapeutic opportunities
EM Porto, AC Komor, IM Slaymaker… - Nature Reviews Drug …, 2020 - nature.com
Base editing—the introduction of single-nucleotide variants (SNVs) into DNA or RNA in
living cells—is one of the most recent advances in the field of genome editing. As around …
living cells—is one of the most recent advances in the field of genome editing. As around …
Electron microscopy studies of soft nanomaterials
This review highlights recent efforts on applying electron microscopy (EM) to soft (including
biological) nanomaterials. We will show how developments of both the hardware and …
biological) nanomaterials. We will show how developments of both the hardware and …
[HTML][HTML] Nano-based drug delivery systems: Conventional drug delivery routes, recent developments and future prospects
Drug delivery can be defined as the group of approaches a drug or pharmacologically active
agent can be transported to the target cell to treat disease or health issue. Conventional …
agent can be transported to the target cell to treat disease or health issue. Conventional …
Self-assembling nucleic acid nanostructures functionalized with aptamers
A Krissanaprasit, CM Key, S Pontula… - Chemical …, 2021 - ACS Publications
Researchers have worked for many decades to master the rules of biomolecular design that
would allow artificial biopolymer complexes to self-assemble and function similarly to the …
would allow artificial biopolymer complexes to self-assemble and function similarly to the …
Rapid prototyping of arbitrary 2D and 3D wireframe DNA origami
Wireframe DNA origami assemblies can now be programmed automatically from the top-
down using simple wireframe target geometries, or meshes, in 2D and 3D, using either rigid …
down using simple wireframe target geometries, or meshes, in 2D and 3D, using either rigid …
Ultrafast dense DNA functionalization of quantum dots and rods for scalable 2D array fabrication with nanoscale precision
Scalable fabrication of two-dimensional (2D) arrays of quantum dots (QDs) and quantum
rods (QRs) with nanoscale precision is required for numerous device applications. However …
rods (QRs) with nanoscale precision is required for numerous device applications. However …
Nanoscale 3D spatial addressing and valence control of quantum dots using wireframe DNA origami
Control over the copy number and nanoscale positioning of quantum dots (QDs) is critical to
their application to functional nanomaterials design. However, the multiple non-specific …
their application to functional nanomaterials design. However, the multiple non-specific …
3D RNA-scaffolded wireframe origami
Hybrid RNA: DNA origami, in which a long RNA scaffold strand folds into a target
nanostructure via thermal annealing with complementary DNA oligos, has only been …
nanostructure via thermal annealing with complementary DNA oligos, has only been …