DNA origami

S Dey, C Fan, KV Gothelf, J Li, C Lin, L Liu… - Nature Reviews …, 2021 - nature.com
Biological materials are self-assembled with near-atomic precision in living cells, whereas
synthetic 3D structures generally lack such precision and controllability. Recently, DNA …

Functionalizing DNA origami to investigate and interact with biological systems

GA Knappe, EC Wamhoff, M Bathe - Nature Reviews Materials, 2023 - nature.com
DNA origami has emerged as a powerful method to generate DNA nanostructures with
dynamic properties and nanoscale control. These nanostructures enable complex …

Base editing: advances and therapeutic opportunities

EM Porto, AC Komor, IM Slaymaker… - Nature Reviews Drug …, 2020 - nature.com
Base editing—the introduction of single-nucleotide variants (SNVs) into DNA or RNA in
living cells—is one of the most recent advances in the field of genome editing. As around …

Electron microscopy studies of soft nanomaterials

Z Lyu, L Yao, W Chen, FC Kalutantirige… - Chemical …, 2023 - ACS Publications
This review highlights recent efforts on applying electron microscopy (EM) to soft (including
biological) nanomaterials. We will show how developments of both the hardware and …

[HTML][HTML] Nano-based drug delivery systems: Conventional drug delivery routes, recent developments and future prospects

A Sultana, M Zare, V Thomas, TSS Kumar… - Medicine in Drug …, 2022 - Elsevier
Drug delivery can be defined as the group of approaches a drug or pharmacologically active
agent can be transported to the target cell to treat disease or health issue. Conventional …

Self-assembling nucleic acid nanostructures functionalized with aptamers

A Krissanaprasit, CM Key, S Pontula… - Chemical …, 2021 - ACS Publications
Researchers have worked for many decades to master the rules of biomolecular design that
would allow artificial biopolymer complexes to self-assemble and function similarly to the …

Rapid prototyping of arbitrary 2D and 3D wireframe DNA origami

H Jun, X Wang, MF Parsons, WP Bricker… - Nucleic acids …, 2021 - academic.oup.com
Wireframe DNA origami assemblies can now be programmed automatically from the top-
down using simple wireframe target geometries, or meshes, in 2D and 3D, using either rigid …

Ultrafast dense DNA functionalization of quantum dots and rods for scalable 2D array fabrication with nanoscale precision

C Chen, X Luo, AEK Kaplan, MG Bawendi… - Science …, 2023 - science.org
Scalable fabrication of two-dimensional (2D) arrays of quantum dots (QDs) and quantum
rods (QRs) with nanoscale precision is required for numerous device applications. However …

Nanoscale 3D spatial addressing and valence control of quantum dots using wireframe DNA origami

C Chen, X Wei, MF Parsons, J Guo, JL Banal… - Nature …, 2022 - nature.com
Control over the copy number and nanoscale positioning of quantum dots (QDs) is critical to
their application to functional nanomaterials design. However, the multiple non-specific …

3D RNA-scaffolded wireframe origami

MF Parsons, MF Allan, S Li, TR Shepherd… - Nature …, 2023 - nature.com
Hybrid RNA: DNA origami, in which a long RNA scaffold strand folds into a target
nanostructure via thermal annealing with complementary DNA oligos, has only been …