Enterococcus faecalis and Enterococcus faecium are Gram-positive commensal gut bacteria
that can also cause fatal infections. To study clinically relevant multi-drug resistant E …

Invasive fungal pathogens are major causes of human mortality and morbidity,. Although
numerous secreted effector proteins that reprogram innate immunity to promote virulence …

The basidiomycetous yeasts of the Cryptococcus neoformans and Cryptococcus gattii
species complexes (CNSC and CGSC respectively) are the causative agents of …

The pathogenic fungus Cryptococcus neoformans exhibits morphological changes in cell
size during lung infection, producing both typical size 5 to 7 μm cells and large titan cells (> …

Cryptococcus neoformans is a fungal pathogen that claims hundreds of thousands of lives
annually. Targeted genetic manipulation through biolistic transformation in C. neoformans …

Calcineurin is a highly conserved Ca2+/calmodulin-dependent serine/threonine-specific
protein phosphatase that orchestrates cellular Ca2+ signaling responses. In Cryptococcus …

Cryptococcus neoformans infections cause approximately 15% of AIDS-related deaths
owing to a combination of limited antifungal therapies and drug resistance. A collection of …

Cryptococcus neoformans, the most common cause of fungal meningitis, is a basidiomycete
haploid budding yeast with a complete sexual cycle. Genome modification by homologous …

Resistance to fluconazole (FLC), the most widely used antifungal drug, is typically achieved
by altering the azole drug target and/or drug efflux pumps. Recent reports have suggested a …

The majority of invasive human fungal pathogens gain access to their human hosts via the
inhalation of spores from the environment into the lung, but relatively little is known about …