[HTML][HTML] Brain concentrations of glutamate and GABA in human epilepsy: A review
GL Sarlo, KF Holton - Seizure, 2021 - Elsevier
An imbalance between excitation and inhibition has been a longstanding proposed
mechanism regarding ictogenesis and epileptogenesis. This imbalance is related to …
mechanism regarding ictogenesis and epileptogenesis. This imbalance is related to …
A review of molecular imaging of glutamate receptors
JH Kim, J Marton, SM Ametamey, P Cumming - Molecules, 2020 - mdpi.com
Molecular imaging with positron emission tomography (PET) and single photon emission
computed tomography (SPECT) is a well-established and important in vivo technique to …
computed tomography (SPECT) is a well-established and important in vivo technique to …
N-methyl-D-aspartate receptor availability in first-episode psychosis: a PET-MR brain imaging study
K Beck, A Arumuham, M Veronese… - Translational …, 2021 - nature.com
N-methyl-D-aspartate receptor (NMDAR) hypofunction is hypothesised to underlie psychosis
but this has not been tested early in illness. To address this, we studied 40 volunteers (21 …
but this has not been tested early in illness. To address this, we studied 40 volunteers (21 …
Tailoring materials for epilepsy imaging: from biomarkers to imaging probes
Excising epileptic foci (EF) is the most efficient approach for treating drug‐resistant epilepsy
(DRE). However, owing to the vast heterogeneity of epilepsies, EF in one‐third of patients …
(DRE). However, owing to the vast heterogeneity of epilepsies, EF in one‐third of patients …
NMDA receptor ion channel activation detected in vivo with [18F]GE-179 PET after electrical stimulation of rat hippocampus
The positron emission tomography (PET) tracer [18F] GE-179 binds to the phencyclidine
(PCP) site in the open N-methyl-D-aspartate receptor ion channel (NMDAR-IC). To …
(PCP) site in the open N-methyl-D-aspartate receptor ion channel (NMDAR-IC). To …
[HTML][HTML] Selecting the Best Animal Model of Parkinson's Disease for Your Research Purpose: Insight from in vivo PET Imaging Studies
CC Real, KH Binda, MB Thomsen… - Current …, 2023 - ncbi.nlm.nih.gov
Parkinson's disease (PD) is a debilitating neurodegenerative multisystem disorder leading
to motor and non-motor symptoms in millions of individuals. Despite intense research, there …
to motor and non-motor symptoms in millions of individuals. Despite intense research, there …
Modulation of the rat hippocampal‐cortex network and episodic‐like memory performance following entorhinal cortex stimulation
Y Jiang, DF Liu, X Zhang, HG Liu… - CNS neuroscience & …, 2022 - Wiley Online Library
Aims Entorhinal cortex (EC) deep brain stimulation (DBS) has shown a memory
enhancement effect. However, its brain network modulation mechanisms remain unclear …
enhancement effect. However, its brain network modulation mechanisms remain unclear …
The association between N-methyl-d-aspartate receptor availability and glutamate levels: A multi-modal PET-MR brain imaging study in first-episode psychosis and …
Background: Evidence from post-mortem studies and in vivo imaging studies suggests there
may be reduced N-methyl-d-aspartate receptor (NMDAR) levels in the hippocampus in …
may be reduced N-methyl-d-aspartate receptor (NMDAR) levels in the hippocampus in …
Pharmacological Characterization of [18F]-FNM and Evaluation of NMDA Receptors Activation in a Rat Brain Injury Model
M Beaurain, F Talmont, D Pierre, P Péran… - Molecular Imaging and …, 2023 - Springer
Purpose NMDA receptors (NMDARs) dysfunction plays a central role in the physiopathology
of psychiatric and neurodegenerative disorders whose mechanisms are still poorly …
of psychiatric and neurodegenerative disorders whose mechanisms are still poorly …
Activated N‐methyl‐D‐aspartate receptor ion channels detected in focal epilepsy with [18F]GE‐179 positron emission tomography
AK Vibholm, MJ Dietz, S Beniczky, J Christensen… - …, 2021 - Wiley Online Library
Objective Imaging activated glutamate N‐methyl‐D‐aspartate receptor ion channels
(NMDAR‐ICs) using positron emission tomography (PET) has proved challenging due to …
(NMDAR‐ICs) using positron emission tomography (PET) has proved challenging due to …