Lipopolysaccharide biosynthesis in Pseudomonas aeruginosa

JD King, D Kocíncová, EL Westman… - Innate …, 2009 - journals.sagepub.com
Pseudomonas aeruginosa causes serious nosocomial infections, and an important
virulence factor produced by this organism is lipopolysaccharide (LPS). This review …

Natural‐product sugar biosynthesis and enzymatic glycodiversification

CJ Thibodeaux, CE Melançon III… - Angewandte Chemie …, 2008 - Wiley Online Library
Many biologically active small‐molecule natural products produced by microorganisms
derive their activities from sugar substituents. Changing the structures of these sugars can …

Short‐chain dehydrogenases/reductases (SDRs) Coenzyme‐based functional assignments in completed genomes

Y Kallberg, U Oppermann, H Jörnvall… - European Journal of …, 2002 - Wiley Online Library
Short‐chain dehydrogenases/reductases (SDRs) are enzymes of great functional diversity.
Even at sequence identities of typically only 15–30%, specific sequence motifs are …

Cloning and functional characterization of the Pseudomonas aeruginosa rhlC gene that encodes rhamnosyltransferase 2, an enzyme responsible for di‐rhamnolipid …

R Rahim, UA Ochsner, C Olvera… - Molecular …, 2001 - Wiley Online Library
Pseudomonas aeruginosa is an opportunistic pathogen capable of producing a wide variety
of virulence factors, including extracellular rhamnolipids and lipopolysaccharide …

[HTML][HTML] Gene regulation of rhamnolipid production in Pseudomonas aeruginosa–a review

RS Reis, AG Pereira, BC Neves, DMG Freire - Bioresource technology, 2011 - Elsevier
Pseudomonas aeruginosa produces abundant levels of rhamnolipid biosurfactants which
exhibit remarkable chemical and physical characteristics, making these compounds …

The rhamnose pathway

MF Giraud, JH Naismith - Current opinion in structural biology, 2000 - Elsevier
l-Rhamnose is a deoxy sugar found widely in bacteria and plants. Evidence continues to
emerge about its essential role in many pathogenic bacteria. The crystal structures of two of …

Decaprenylphosphoryl Arabinofuranose, the Donor of the d-Arabinofuranosyl Residues of Mycobacterial Arabinan, Is Formed via a Two-Step Epimerization of …

K Mikušová, H Huang, T Yagi, M Holsters… - Journal of …, 2005 - Am Soc Microbiol
The major cell wall polysaccharide of mycobacteria is a branched-chain arabinogalactan in
which arabinan chains are attached to the 5 carbon of some of the 6-linked galactofuranose …

MUCILAGE-MODIFIED4 encodes a putative pectin biosynthetic enzyme developmentally regulated by APETALA2, TRANSPARENT TESTA GLABRA1, and GLABRA2 …

TL Western, DS Young, GH Dean, WL Tan… - Plant …, 2004 - academic.oup.com
The Arabidopsis seed coat epidermis undergoes a complex process of differentiation that
includes the biosynthesis and secretion of large quantities of pectinaceous mucilage …

[HTML][HTML] The structural basis of the catalytic mechanism and regulation of glucose-1-phosphate thymidylyltransferase (RmlA)

W Blankenfeldt, M Asuncion, JS Lam… - The EMBO journal, 2000 - embopress.org
The synthesis of deoxy-thymidine di-phosphate (dTDP)–L-rhamnose, an important
component of the cell wall of many microorganisms, is a target for therapeutic intervention …

Functional analysis of Arabidopsis thaliana RHM2/MUM4, a multidomain protein involved in UDP-D-glucose to UDP-L-rhamnose conversion

T Oka, T Nemoto, Y Jigami - Journal of Biological Chemistry, 2007 - ASBMB
UDP-l-rhamnose is required for the biosynthesis of cell wall rhamnogalacturonan-I,
rhamnogalacturonan-II, and natural compounds in plants. It has been suggested that the …