Molecular imaging and disease theranostics with renal-clearable optical agents
P Cheng, K Pu - Nature Reviews Materials, 2021 - nature.com
Optical imaging in disease diagnosis and treatment benefits from high spatiotemporal
resolution and the availability of numerous optical agents. However, many optical imaging …
resolution and the availability of numerous optical agents. However, many optical imaging …
From animal poisons and venoms to medicines: achievements, challenges and perspectives in drug discovery
KCF Bordon, CT Cologna, EC Fornari-Baldo… - Frontiers in …, 2020 - frontiersin.org
Animal poisons and venoms are comprised of different classes of molecules displaying wide-
ranging pharmacological activities. This review aims to provide an in-depth view of toxin …
ranging pharmacological activities. This review aims to provide an in-depth view of toxin …
Fluorescent chemical probes for accurate tumor diagnosis and targeting therapy
Surgical resection of solid tumors is currently the gold standard and preferred therapeutic
strategy for cancer. Chemotherapy drugs also make a significant contribution by inhibiting …
strategy for cancer. Chemotherapy drugs also make a significant contribution by inhibiting …
A neurocentric perspective on glioma invasion
VA Cuddapah, S Robel, S Watkins… - Nature Reviews …, 2014 - nature.com
Malignant gliomas are devastating tumours that frequently kill patients within 1 year of
diagnosis. The major obstacle to a cure is diffuse invasion, which enables tumours to …
diagnosis. The major obstacle to a cure is diffuse invasion, which enables tumours to …
Molecular interactions in organic nanoparticles for phototheranostic applications
Optical and photonic technologies play an important role in human progress. The bending of
light to our will has not only enabled our biological self-discovery, but has also allowed us to …
light to our will has not only enabled our biological self-discovery, but has also allowed us to …
CAR T cells for brain tumors: Lessons learned and road ahead
Malignant brain tumors, including glioblastoma, represent some of the most difficult to treat
of solid tumors. Nevertheless, recent progress in immunotherapy, across a broad range of …
of solid tumors. Nevertheless, recent progress in immunotherapy, across a broad range of …
Chlorotoxin-directed CAR T cells for specific and effective targeting of glioblastoma
D Wang, R Starr, WC Chang, B Aguilar… - Science translational …, 2020 - science.org
Although chimeric antigen receptor (CAR) T cells have demonstrated signs of antitumor
activity against glioblastoma (GBM), tumor heterogeneity remains a critical challenge. To …
activity against glioblastoma (GBM), tumor heterogeneity remains a critical challenge. To …
[HTML][HTML] Peptide therapeutics from venom: Current status and potential
MW Pennington, A Czerwinski, RS Norton - Bioorganic & medicinal …, 2018 - Elsevier
Peptides are recognized as being highly selective, potent and relatively safe as potential
therapeutics. Peptides isolated from the venom of different animals satisfy most of these …
therapeutics. Peptides isolated from the venom of different animals satisfy most of these …
Protein− nanoparticle interactions: opportunities and challenges
In recent years, the fabrication of nanomaterials and exploration of their properties have
attracted the attention of all branches of science, such as physics, chemistry, biology, and …
attracted the attention of all branches of science, such as physics, chemistry, biology, and …
Fluorescence-guided surgery with live molecular navigation—a new cutting edge
QT Nguyen, RY Tsien - Nature reviews cancer, 2013 - nature.com
A glowing new era in cancer surgery may be dawning. Using fluorescently labelled markers,
surgical molecular navigation means that tumours and nerves can be displayed in real time …
surgical molecular navigation means that tumours and nerves can be displayed in real time …