Wall teichoic acid in Staphylococcus aureus host interaction

R van Dalen, A Peschel, NM van Sorge - Trends in microbiology, 2020 - cell.com
Staphylococcus aureus is a major opportunistic human pathogen that frequently causes
disease in community and hospital settings. Nasal colonization is an important risk factor for …

[HTML][HTML] From structure to function–Ligand recognition by myeloid C-type lectin receptors

S Fischer, F Stegmann, VS Gnanapragassam… - Computational and …, 2022 - Elsevier
The relevance of protein-glycan interactions in immunity has long been underestimated. Yet,
the immune system possesses numerous classes of glycan-binding proteins, so-called …

Dismantling the bacterial glycocalyx: Chemical tools to probe, perturb, and image bacterial glycans

P Luong, DH Dube - Bioorganic & medicinal chemistry, 2021 - Elsevier
The bacterial glycocalyx is a quintessential drug target comprised of structurally distinct
glycans. Bacterial glycans bear unusual monosaccharide building blocks whose proper …

Simplifying the detection and monitoring of protein glycosylation during in vitro glycoengineering

MJ Saunders, RJ Woods, L Yang - Scientific Reports, 2023 - nature.com
The majority of mammalian proteins are glycosylated, with the glycans serving to modulate a
wide range of biological activities. Variations in protein glycosylation can have dramatic …

C-Type lectins in veterinary species: recent advancements and applications

DL Lindenwald, B Lepenies - International journal of molecular sciences, 2020 - mdpi.com
C-type lectins (CTLs), a superfamily of glycan-binding receptors, play a pivotal role in the
host defense against pathogens and the maintenance of immune homeostasis of higher …

High sensitivity glycomics in biomedicine

GSM Lageveen‐Kammeijer, B Kuster… - Mass spectrometry …, 2022 - Wiley Online Library
Many analytical challenges in biomedicine arise from the generally high heterogeneity and
complexity of glycan‐and glycoconjugate‐containing samples, which are often only …

[HTML][HTML] Insights into Glycobiology and the Protein-Glycan Interactome Using Glycan Microarray Technologies

J Heimburg-Molinaro, AY Mehta, CA Tilton… - Molecular & Cellular …, 2024 - Elsevier
Glycans linked to proteins and lipids and also occurring in free forms have many functions,
and these are partly elicited through specific interactions with glycan-binding proteins …

The unique 3D arrangement of macrophage galactose lectin enables Escherichia coli lipopolysaccharide recognition through two distinct interfaces

M Abbas, M Maalej, F Nieto-Fabregat, M Thépaut… - PNAS …, 2023 - academic.oup.com
Lipopolysaccharides are a hallmark of gram-negative bacteria, and their presence at the cell
surface is key for bacterial integrity. As surface-exposed components, they are recognized …

Rapid Evolution of Glycan Recognition Receptors Reveals an Axis of Host–Microbe Arms Races beyond Canonical Protein–Protein Interfaces

ZA Hilbert, PE Haffener, HJ Young… - Genome Biology and …, 2023 - academic.oup.com
Detection of microbial pathogens is a primary function of many mammalian immune
proteins. This is accomplished through the recognition of diverse microbial-produced …

Molecular and functional characterization of a ladderlectin-like molecule from ayu (Plecoglossus altivelis)

W Wang, MY Liu, CJ Fei, CH Li, J Chen - Fish & Shellfish Immunology, 2022 - Elsevier
Ladderlectin is a member of C-type lectins (CTLs) in teleost fish and involved in innate
immune defense. In this study, ayu (Plecoglossus altivelis) ladderlecin-like (PaLL-like) …